Electrochemical modulation of mechanical properties of glycolated polythiophenes

Abdel Aziz, Ilaria; Gladisch, Johannes; Musumeci, Chiara; Moser, Maximilian; Griggs, Sophie; Kousseff, Christina J.; Berggren, Magnus; McCulloch, Iain; Stavrinidou, Eleni

doi:10.1039/d3mh01827j

Mater. Horiz.

2024

DOI: 10.1039/d3mh01827j

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Electrochemical modulation of mechanical properties of glycolated polythiophenes

Ilaria Abdel Aziz,

Johannes Gladisch,

Chiara Musumeci

et al.

Abstract: Electrochemical doping of organic mixed ionic-electronic conductors is key for modulating their conductivity, charge storage and volume enabling high performing bioelectronic devices such as recording and stimulating electrodes, transistors-based sensors...

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2024

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Cited by 2 publications

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Conducting Polymers for In Situ Drug Release Triggered via Electrical Stimulus

Pérez-Nava,

González-Campos,

Frontana-Uribe

2024

ACS Appl. Polym. Mater.

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Conducting polymers (CPs) are a unique type of polymer that exhibit metal-like features. Their ability to undergo reversible redox conversion, in addition to their optical and electronic properties, have enhanced the use of CPs in the development of advanced materials for technological applications, mainly focused on the energy field. However, during the last 15 years, increasing interest has been focused on biomedical and pharmaceutical applications of CPs. The development of CPs-based biocomposites for drug release takes advantage of the reversible redox behavior of CPs, allowing an accurate control of therapeutic agents and other bioactive molecule release profiles, triggered by an external stimulus. This Review discusses the development of drug delivery systems based on CPs. Encompassing intrinsic features, such as physicochemical aspects, electrical ability, and conducting mechanism involved in the release of therapeutic agents driven by electrochemical stimuli. A detailed description of the electrochemical drug-loading, methods of fabrication, and characterization of innovative CPs-based drug delivery platforms is provided. A comparative analysis of polymerization methods is presented to guide researchers in the method selection. Finally, application of CPs on drug release, and cell response, is discussed in terms of their intrinsic properties, which enhance their pharmaceutical applications.

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Conducting Polymers for In Situ Drug Release Triggered via Electrical Stimulus

Pérez-Nava,

González-Campos,

Frontana-Uribe

2024

ACS Appl. Polym. Mater.

View full text Add to dashboard Cite

show abstract

Drug delivery via a 3D electro-swellable conjugated polymer hydrogel

Abdel Aziz,

Gladisch,

Griggs

et al. 2024

J. Mater. Chem. B

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Electrochemical modulation of mechanical properties of glycolated polythiophenes

Abstract: Electrochemical doping of organic mixed ionic-electronic conductors is key for modulating their conductivity, charge storage and volume enabling high performing bioelectronic devices such as recording and stimulating electrodes, transistors-based sensors...

Cited by 2 publications

References 57 publications

Conducting Polymers for In Situ Drug Release Triggered via Electrical Stimulus

Conducting Polymers for In Situ Drug Release Triggered via Electrical Stimulus

Drug delivery via a 3D electro-swellable conjugated polymer hydrogel

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