Electrochemical detection of hepatitis B and papilloma virus DNAs using SWCNT array coated with gold nanoparticles

Wang, Shun; Li, Ling; Jin, Huile; Yang, Ting; Bao, Weiwei; Huang, Shaoming; Wang, Jichang

doi:10.1016/j.bios.2012.08.021

Cited by 90 publications

(46 citation statements)

References 31 publications

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“…Hence, since the initial method of attaching individual nanoparticles to oligonucleotide sequences (Authier et al, 2000;Wang et al, 2001a), strategies have been developed to attach nanoparticle assemblies. This has been through loading the nanoparticles on a solid support such as latex particles (Dong et al, 2010;Pinijsuwan et al, 2008) or carbon nanotubes (Wang et al, 2003b;Wang et al, 2013), the use of catalytic reduction to increase the quantity of nanomaterial on the label (Taton, et al, 2000;Wang et al, 2001b;Lin et al, 2011), the association of positively charged Ag nanoparticles with the negative phosphate groups of DNA , or the formation of nanoparticle aggregates, caused by target -probe binding (Li et al, 2010). We previously achieved a LOD of approx.…”

Section: Introductionmentioning

confidence: 97%

Highly sensitive electrochemical detection of genomic DNA based on stem loop probes structured for magnetic collection and measurement via metalised hollow polyelectrolyte shells

Khunrattanaporn

Rijiravanich

Somasundrum

et al. 2015

Biosensors and Bioelectronics

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Section: Introductionmentioning

confidence: 97%

Highly sensitive electrochemical detection of genomic DNA based on stem loop probes structured for magnetic collection and measurement via metalised hollow polyelectrolyte shells

Khunrattanaporn

Rijiravanich

Somasundrum

et al. 2015

Biosensors and Bioelectronics

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“…The electrochemical biosensors are promising diagnostic techniques for HPV, because of their tendency to miniaturization and due to their fast response, simplicity, and low cost instrumentation [88]. Although the regeneration of the sensor platform might minimize the cost of the analysis, only a few publications report reusable electrochemical biosensors [28,32].…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

“…From the presented alternatives, we highlight the use of nanomaterials, particularly carbon nanotubes and gold nanoparticles, as strategic components to improve the analytical performance of electrochemical biosensors [38,39,68,89]. The cited nanomaterials exhibit not only combined dielectric and optical properties but also a high surfaceto-volume ratio, biocompatibility, and high conductivity, allowing direct charge transfer between the biomolecule and the electrode surface [90][91][92].…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

“…The strategies to obtain these biosensors combine the specificity of the biological probe with the analytical capacity of the transduction methods [65,66]. In addition, materials at the nanometer scale as nanoparticles [67], nanotubes [28], nanofibers [68], and nanocomposites [69] have been used to achieve the nanostructuration of these devices. The diversity of structures provides tailored interfacial modification alternatives with the purpose of amplifying the analytical signal and increasing the sensibility of the biosensor [63].…”

Section: Biosensors For Hpv As Alternative Diagnostic Toolsmentioning

confidence: 99%

“…Interestingly, the transducer of the platform was designed from single walled carbon nanotube arrays coated with gold nanoparticles, atop of which the self-assembly of single-stranded DNA probe was promoted. Electrochemical impedance was used to verify the high sensitivity, great stability, and good regeneration ability of the biosensor with a detection limit up to one attomole of HPV16 DNA [89].…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

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Trends in Biosensors for HPV: Identification and Diagnosis

et al. 2015

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The conventional methodologies used for the detection of human papillomavirus (HPV) present actually robust and reproducible advantages. However, at the same time, they involve complex protocols that sometimes are difficult to popularize. Over the first half of XX century, the adequate treatment of complex and delicate processes from a simple instrumental base seemed a fundamental and intrinsic contradiction. However, interdisciplinary trends have allowed the manipulation of tissues, proteins, and nucleic acids through innovative increasingly smaller devices. The proper diagnosis of HPV has seen great advances since biosensor researchers are employing its virus strains as models to study the interactions between the biorecognition element and the transducer. Additionally, all recent improvements and trends that material sciences, biotechnology, and data processing scientists excel for biosensors can be applied for the HPV detection platforms. In this review, we highlight the recent trends on materials, nanomaterials, and transducers for the specific detection and differentiation of HPV strains. The most influential methods for the detection and identification of these papillomaviruses include optical, electrochemical, and piezoelectric transducers; we will visit their sensibility and advantages. Additionally, we highlight the factors that contributed to the increasing importance of these biodevices as potential substitutes to conventional diagnostic methods.

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Recent Advances in Nanomaterials‐Based FETs for SARS‐CoV‐2 (COVID‐19 Virus) Diagnosis

Aftab

Iqbal

Hussain

et al. 2023

Adv Funct Materials

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The emergence of infectious diseases that are quickly spreading, like the coronavirus (COVID-19), necessitates the development of efficient biosensors that can quickly detect and identify pathogens. It is essential to create sensitive virus detection methods in order to stop a virus from spreading throughout the world. It is determined that field-effect transistors (FETs) made of nanomaterials are potential candidates for rapid virus identification due to how easily the electronic transport characteristics of such an atomically thin nanomaterial can be affected by perturbations. Various FETs in this review article are investigated that are based on nanoparticles, carbon nanotubes (CNT), graphene, graphene-oxide, and semiconducting transition metal dichalcogenides (TMDs) WSe 2 in order to show that they are promising biosensors in regards to quickly and precisely detect COVID-19. The conjugation of nanomaterials with proteins enables the direct delivery of antiviral agents to the host cells. This method also minimizes the off-target effects and enables the targeted interactions. This mechanism has produced encouraging results in regards to sensing or treating COVID-19. The high surface area and extremely small size of nanomaterials make them crucial in regards to the development of new detection methods. The point-of-care test method of detection is quick, simple, and user-friendly, and it only requires a small amount of a patient's blood. It does not require a laboratory or trained professionals. This overview of the current research that is conducted on nanomaterials will prove to be useful in the process of formulating strategies for the diagnosis, treatment, and vaccination of viruses in opinion. Finally, the conclusion of this review provides a summary of the current challenges and the future prospects.

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Electrochemical detection of hepatitis B and papilloma virus DNAs using SWCNT array coated with gold nanoparticles

Cited by 90 publications

References 31 publications

Highly sensitive electrochemical detection of genomic DNA based on stem loop probes structured for magnetic collection and measurement via metalised hollow polyelectrolyte shells

Highly sensitive electrochemical detection of genomic DNA based on stem loop probes structured for magnetic collection and measurement via metalised hollow polyelectrolyte shells

Trends in Biosensors for HPV: Identification and Diagnosis

Recent Advances in Nanomaterials‐Based FETs for SARS‐CoV‐2 (COVID‐19 Virus) Diagnosis

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