Electrochemical Behaviour of Dopamine on A Glassy Carbon Electrode Modified by Graphene Chitosan Copper Composite

Abstract

Graphene is a hexagonal honeycombed network of carbon atoms arranged in a single layer which is the fundamental building block of all graphitic materials. The novel properties associated with graphene offer many advantages for electrochemical applications. The present work aims at preparing graphene copper chitosan composite for the voltametric determination of the most prominent catechol amine dopamine. Modified Hummers method was followed for Graphite oxide (GO) preparation. GO and CuSO 4 .5H 2 O were brought into an aqueous solution, to this chitosan was added which was refluxed and subsequently reduced to obtain the required graphene -copper composite. The composite was characterized structurally and morphologically by XRD, SEM and it was used for modifying a glassy carbon electrode. The modified electrode was used for sensing dopamine by CV and DPV. The effect of scan rate and pH on the performance of modified glassy carbon electrode was evaluated. The fabricated electrode was also evaluated for the simultaneous determination of dopamine and uric acid. This electrochemical sensor was found to be most sensitive and reliable at the physiological pH 7.