Electrochemical Behaviour of 4-Tertbutylcyclohexanone Semicarbazone and its Co(II) Complex

Abstract

The electrochemical behaviour of 4-tertbutylcyclohexanone semicarbazone (TBCHSC) and its Co(II) complex was investigated by a glassy carbon electrode, cyclic voltammetry technique. Semicarbazone synthesized from the condensation of 4tertbutylcyclohexanone and semicarbazide hydrochloride (1:1 molar ratio) was further treated with cobalt(II) acetate (2:1 molar ratio), to form the Co(II)-semicarbazone complex. The semicarbazone was studied in buffer solutions (Britton-Robinson universal buffer and phosphate buffer), with a pH in the range of 3 to 11. The reduction process was found to be irreversible and diffusion controlled, for both semicarbazone and its Co(II) complex. The effects of change on the sweep rate, concentration, pH and solvent were evaluated. The semicarbazone reduction mechanism was suggested on the basis of the obtained results. Kinetic parameters, such as charge transfer coefficient (αn), diffusion coefficient (D0 1/2), and rate constant (k°f,h), were calculated from cyclic voltammetric measurements. Semicarbazone and its Co(II) complex were tested against bacterial and fungal species. The metal complex had higher activity than the free ligand.

Electrochemical and Biological Studies of Synthesized Schiff base and It's Zinc Complex

“…At pH 5.8, the ligand showed cathodic reduction peaks with 50-250(mV/s) sweep rates from -829.46 mV to -897.38 mV in methanol-phosphate buffer. So, the reduction signal shifted towards high negative potential values with faster scan rate 15 . In Fig.…”