Electrocatalytical oxidation and sensitive determination of acetaminophen on glassy carbon electrode modified with graphene–chitosan composite

Zheng, Meixia; Gao, Feng; Wang, Qingxiang; Cai, Xili; Jiang, Shu-Lian; Huang, Linjun; Gao, Fei

doi:10.1016/j.msec.2012.12.055

Cited by 86 publications

(32 citation statements)

References 40 publications

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“…It has been previously shown that the oxidation of acetaminophen (ACOP) is pH dependent [24,38] with slope values close to the Nernstian value, 59 mV pH −1 , indicating an equal number of electrons and protons participating in the electrochemical process. The number of electrons has been calculated [8] and assumed [15,24] to be 2, and according to this, the proposed reaction mechanism occurring at the modified electrode is presented in Scheme 2.…”

Section: Acetaminophen Determinationmentioning

confidence: 98%

“…The analytical determination of ACOP was investigated by oxidation in 0.1 M NaPB pH 7.0, which has been chosen as optimum in other studies [23,38], and differential pulse It has been previously remarked that acetaminophen detection at graphene-and CNT-modified electrodes is partly a surface-confined process [24] and that determination depends on the accumulation time but is independent of the applied potential in the potential range tested [39][40][41]. In [11], it appeared that electrode polarization during the measurement also plays a role in increasing the concentration near the electrode surface and leads to signal enhancement, as well as ACOP adsorption.…”

Section: Acetaminophen Determinationmentioning

confidence: 99%

“…DPV at MWCNT/PTH/CFE and PTH/MWCNT/CFE both exhibited one peak, corresponding to oxidation of acetaminophen to N-acetyl-p-quinoneimine [38], which appears at 0.337 V vs. SCE. The peak current increased linearly with increase of acetaminophen concentration, over the concentration range from 25 to 250 μM.…”

Section: Acetaminophen Determinationmentioning

confidence: 99%

See 2 more Smart Citations

Poly(thionine)-carbon nanotube modified carbon film electrodes and application to the simultaneous determination of acetaminophen and dipyrone

Ghica

Ferreira

Brett

2015

J Solid State Electrochem

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Multi-walled carbon nanotube (MWCNT)-poly(thionine) (PTH) nanostructures were formed on carbon film electrodes (CFE), the polymer film being formed beneath or on top of MWCNT, to give two different sensor architectures, PTH/MWCNT/CFE or MWCNT/PTH/CFE. Characterization of the novel nanostructures was carried out by cyclic voltammetry, electrochemical impedance spectroscopy and scanning electron microscopy. The modified electrodes were then used for sensing acetaminophen (ACOP) and dipyrone by differential pulse voltammetry and fixedpotential amperometry independently and simultaneously. Analytical parameters were determined and the results compared with similarly modified electrodes reported in the literature. An interference study as well as recovery measurements in pharmaceutical samples was successfully performed.

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Section: Acetaminophen Determinationmentioning

confidence: 98%

Section: Acetaminophen Determinationmentioning

confidence: 99%

See 1 more Smart Citation

Poly(thionine)-carbon nanotube modified carbon film electrodes and application to the simultaneous determination of acetaminophen and dipyrone

Ghica

Ferreira

Brett

2015

J Solid State Electrochem

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“…stripped out from graphite material, has attracted enormous attention since its discovery in 2004 [18]. Owing to its unique 2D structure, being ultra thin, with high strength, and its conductivity, graphene has shown great potential in many areas of application, for instance batteries [19], nanoelectronics [20], super capacitors [21], and ultra-sensitive sensors [22][23][24]. As a result, recently, the application of graphene-based nanocomposite-modified electrodes to detect acetaminophen attracted researchers of great interest since acetaminophen has a wide application in our lives [17].…”

Section: Introductionmentioning

confidence: 99%

Ultra-sensitive film sensor based on Al2O3–Au nanoparticles supported on PDDA-functionalized graphene for the determination of acetaminophen

Sun

Wang

et al. 2016

Anal Bioanal Chem

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An electrochemical sensor of acetaminophen based on poly(diallyldimethylammonium chloride) (PDDA)-functionalized reduced graphene-loaded Al2O3-Au nanoparticles coated onto glassy carbon electrode (Al2O3-Au/PDDA/reduced graphene oxide (rGO)/glass carbon electrode (GCE)) were prepared by layer self-assembly technique. The as-prepared electrode-modified materials were characterized by scanning electron microscopy, X-ray powder diffraction, and Fourier transform infrared spectroscopy. The electrocatalytic performances of Al2O3-Au/PDDA/rGO-modified glassy carbon electrode toward the acetaminophen were investigated by cyclic voltammetry and differential pulse voltammetry. The modified electrodes of graphene oxide (GO)/GCE, PDDA/rGO/GCE, and Al2O3-Au/PDDA/rGO/GCE were constructed for comparison and learning the catalytic mechanism. The research showed Al2O3-Au/PDDA/rGO/GCE having good electrochemical performance, attributing to the synergetic effect that comes from the special nanocomposite structure and physicochemical properties of Al2O3-Au nanoparticles and graphene. A low detection limit of 6 nM (S/N = 3) and a wide linear detection range from 0.02 to 200 μM (R (2) = 0.9970) was obtained. The preparation of sensor was successfully applied for the detection of acetaminophen in commercial pharmaceutical pills. Graphical abstract Schematic diagram of synthesis of Al2O3-Au/PDDA/rGO/GCE.

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“…Among these methods, voltammetry methods are highly sensitive, selective, measure over a wide linear range, require no sample preparation and are thus less time consuming for the determination of AC. So, a number of modified electrodes have been used for the electrochemical detection of AC, [36][37][38][39][40][41] for example, carbon-coated nickel magnetic nanoparticles modified electrode 40 and Cu(II)-conducting polymer complex modified electrode. 41 A polycationic dye called ammoniated ruthenium oxychloride, also known as ruthenium red (RR), is an inorganic dye.…”

Section: Introductionmentioning

confidence: 99%

Development of Glassy Carbon Electrode Modified with Ruthenium Red-multiwalled Carbon Nanotubes for Simultaneous Determination of Epinephrine and Acetaminophen

2014

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A glassy carbon electrode modified with ruthenium red and functionalized multi-walled carbon nanotube has been developed. The electrochemical response characteristics of the modified electrode toward epinephrine (EP) and acetaminophen (AC) was investigated by differential pulse voltammetry (DPV). Linear calibration plots were obtained over the range of 0.3 -333.3 μM for both EP and AC with sensitivities of 0.221 and 0.174 μA μM -1 for EP and AC, respectively. The detection limits for EP and AC were 0.04 and 0.06 μM, respectively. The diffusion coefficients for the oxidation of EP and AC at the modified electrode were calculated as 2.74 ± 0.05 × 10 -5 and 1.75 ± 0.07 × 10 -5 cm 2 s -1 , respectively. The practical analytical utilities of the modified electrode were demonstrated by the determination of EP and AC in human urine and serum as well as AC tablet samples.

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Electrocatalytical oxidation and sensitive determination of acetaminophen on glassy carbon electrode modified with graphene–chitosan composite

Cited by 86 publications

References 40 publications

Poly(thionine)-carbon nanotube modified carbon film electrodes and application to the simultaneous determination of acetaminophen and dipyrone

Poly(thionine)-carbon nanotube modified carbon film electrodes and application to the simultaneous determination of acetaminophen and dipyrone

Ultra-sensitive film sensor based on Al2O3–Au nanoparticles supported on PDDA-functionalized graphene for the determination of acetaminophen

Development of Glassy Carbon Electrode Modified with Ruthenium Red-multiwalled Carbon Nanotubes for Simultaneous Determination of Epinephrine and Acetaminophen

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