Electrocardiographic changes in dermatomyositis and polymyositis

Dermatomyositis (DM) in adults has a prevalence of 6-7 per 100,000 population per year. This dedicated compact overview was prepared due to an increasing incidence as well as an often underestimated systemic involvement and new developments in myositis-specific antibodies (MSA). The spectrum of clinical dermatological and systemic symptoms is described. Related diagnostic procedures are depicted, and therapeutic regimens based on the German S2k guidelines and the current literature are presented. The urgency of an early diagnosis is emphasized as about 30 % of patients with DM manifest a tumor. Etiopathology is often associated with pulmonary fibrosis, and inflammation of myositis can cause irreversible muscle damage. Clinical signs and correct interpretation of serological markers can deliver valuable information on the extent of DM, and provide an indication for further diagnostic procedures, prognosis and choice of therapy.

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“…with PM than in DM patients [27]. A correlation between ECG abnormalities and disease progression has not been established.…”

Section: Skin Signs Such As Heliotropic Erythemamentioning

confidence: 93%

Update on dermatomyositis in adults

Schlecht

Sunderkötter

Niehaus

et al. 2020

J Deutsche Derma Gesell

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“…Devezy et al. found that in a group of 34 PM patients, VES was diagnosed in two patients based on the resting electrocardiogram (5.9%) (Deveza et al., ). In the study of Taylor et al.…”

Section: Discussionmentioning

confidence: 99%

“…Devezy et al found that in a group of 34 PM patients, VES was diagnosed in two patients based on the resting electrocardiogram (5.9%) (Deveza et al, 2016). In the study of Taylor et al premature ventricular extrasystoles were observed in 69% of patients and 31% of patients reported palpitations as a symptom (Taylor et al, 1993).…”

Section: Case Reportmentioning

confidence: 97%

Symptomatic arrhythmia in the form of multiple premature ventricular extrasystoles as the first symptom of polymyositis

Peregud‐Pogorzelska

Zielska

Kaźmierczak

2018

Noninvasive Electrocardiol

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Polymyositis (PM) is an autoimmune disease characterized by the involvement of multiple internal organs, including the cardiovascular system. The involvement of heart is observed in up to 75% of patients with PM. Conduction and rhythm disorders are one of the most common cardiological abnormalities in these patients. The presented clinical case is the patient where ventricular arrhythmia (in the form of multiple premature ventricular extrasystoles) was the first symptom of polymyositis.

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“…Therefore, all individuals should be referred for cardiac and lung function assessment at the time of diagnosis of SAM, and clinical evaluation, including detailed anamnesis and physical examination is essential [108]. Some tests are recommended, such as electrocardiogram and the evaluation of pulmonary function, to verify cardiac involvement with arrhythmias and conduction abnormalities and impairment of pulmonary function as a reduction in vital capacity (B) [90,112] (C) [85] (D) [113].…”

Section: Literature Review and Analysismentioning

confidence: 99%

The Brazilian Society of Rheumatology recommendations on investigation and diagnosis of systemic autoimmune myopathies

et al. 2019

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Background: This research is recommended by the Myopathy Committee of the Brazilian Society of Rheumatology for the investigation and diagnosis of systemic autoimmune myopathies. Body: A systematic literature review was performed in the Embase, Medline (PubMed) and Cochrane databases, including studies published until October 2018. PRISMA was used for the review, and the articles were evaluated, based on the Oxford levels of evidence. Ten recommendations were developed addressing different aspects of systemic autoimmune myopathy investigation and diagnosis. Conclusions: The European League Against Rheumatism/ American College of Rheumatology (EULAR/ACR) classification stands out for the diagnosis of systemic autoimmune myopathies. Muscular biopsy is essential, aided by muscular magnetic resonance images and electroneuromyography in complementary research. Analysis of the factors related to prognosis with the evaluation of extramuscular manifestations, and comorbidities and intense investigation regarding differential diagnoses are mandatory.

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Electrocardiographic changes in dermatomyositis and polymyositis

Cited by 11 publications

References 17 publications

Update on dermatomyositis in adults

Update on dermatomyositis in adults

Symptomatic arrhythmia in the form of multiple premature ventricular extrasystoles as the first symptom of polymyositis

The Brazilian Society of Rheumatology recommendations on investigation and diagnosis of systemic autoimmune myopathies

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