Electro-spray of high viscous liquids for producing mono-sized spherical alginate beads

Moghadam, Hamid; Samimi, Mohsen; Samimi, Abdolreza; Khorram, Mohammad

doi:10.1016/j.partic.2008.04.005

Cited by 60 publications

(38 citation statements)

References 5 publications

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“…This resulted from its low solubility in THF at this concentration. This result is believed to be because the increased concentration of the pitch solution requires a stronger electrical field to separate the solution into droplets at the tip, at a constant voltage [11]. Therefore, the solution could not be divided into distinct particles.…”

Section: Resultsmentioning

confidence: 99%

Micro-sized carbon with dimple patterns prepared using an electro-spray method

Park¹,

Lee²

2015

Carbon letters

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Carbon micro particles with dimple patterns were produced by electro-spraying a solution of pitch in tetrahydrofuran. Particle formation depended on separation in an electrical field and volatilization of the solvent. More than 80% of the obtained carbon exhibited an average particle size of less than 50 μm. X-ray diffraction analysis suggests that the carbon with dimple patterns has increased crystallinity after heat treatment.

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Section: Resultsmentioning

confidence: 99%

Micro-sized carbon with dimple patterns prepared using an electro-spray method

Park¹,

Lee²

2015

Carbon letters

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“…The effect of needle gauge was investigated in several studies. 61,63,94,96,97 Using a 20G needle, a CS solution was intermittently sputtered while using higher gauge needle of 24G or 26G (smaller inner diameter) resulted in more stable electrospraying with almost spherically shaped particles. 63 In another study, 6 different needles with a range from 18G to 27G were used for electrospraying a PLGA solution.…”

Section: Processerelated Parametersmentioning

confidence: 99%

Pharmaceutical Applications of Electrospraying

Nguyen

Clasen

Mooter

2016

Journal of Pharmaceutical Sciences

153

128

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The electrohydrodynamic atomization technique, or simply called electrospraying, has been extensively studied for biomedical as well as for pharmaceutical applications over the past years. The simplicity, flexibility, and efficiency of producing particles at the microscale or nanoscale, with tailored size, shape, morphology, and microstructure, make electrospraying to become one of the most promising and well-practiced approaches to be applied in many biomedical and pharmaceutical fields, from improving the bioavailability of poorly aqueous soluble drugs, preparing targeted drug delivery systems, and controllable drug release systems to delivering sensitive therapeutic agents such as protein-based drugs or even living cells. Nevertheless, some issues still remain with respect to low throughput as well as the complex interplay between a great number of processing and formulation factors. A comprehensive understanding of these fundamental aspects is essential for the successful application of electrospraying for the production of particulate formulations with desired properties.

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“…This parameter has not been studied in detail in encapsulation of PCM up to now. According to the literature survey, Ghayempour et al [30], Fabien et al [31], Moghadam et al [32], and Huang et al [33] have studied the electrospraying of alginate polymer for encapsulation of different materials, but the optimization of the process parameters using experimental designs has not been mainly considered.…”

Section: Introductionmentioning

confidence: 99%