Electrical effects on the proliferation of living HeLa cells cultured on optically transparent electrode surface

The regulation of cell functions electrically using biodegradable polypyrrole–polylactide conductors

“…For example, Zhao et al [18,19] used an electrical device in which an electrical field (EF) was applied to the culture medium through two salt bridges. Yaoita and Kimura et al [20,21] cultured cells electrically on an indium-tin oxide (ITO)-coated plate as a working electrode, while Schmidt et al [22] applied polypyrrole (PPy)-coated glass as an anode for an electrical cell culture. Although these devices are useful to induce ES in vitro, they can hardly be transformed to stimulate cells cultured on scaffolding materials, either in vitro or in vivo.…”

Sensitivity to electrical stimulation of human immunodeficiency virus type 1 and MAGIC-5 cells

“…In fact, cell membrane damage (Tominaga et al 2007), the regulation of cell proliferation (Kojima et al 1991; Yaoita et al 1990), gene expression of nerve growth factor (Koyama et al 1996; Koyama et al 1997) and neural and osteogenic differentiation (Kimura et al 1998; Mie et al 2003), have been reported in response to low potential loading. Furthermore, the combined effect of low potential stimulation and cisplatin administration caused cell death in HeLa cells (Manabe et al 2004).…”

Manipulating and Monitoring Biomolecular Interactions with Conducting Electroactive Polymers

“…[8] Electrical stimulation of the dorsal nerves of a rat's penis has also been shown to promote erections and reflex ejaculatory responses. [11,12] Platinum electrodes were used by the same group [13] to show that protein (carcinoembryonic antigen) production by mammalian cells (human carcinoma) can be enhanced by applied potential. Aizawa and co-workers have used optically transparent indium tin oxide electrodes to show that electrical stimulation can influence cell morphology [10] and proliferation.…”