Electrical conductivity of skeletal muscle tissue: Experimental results from different musclesin vivo

Gielen, F.L.H.; Jonge, W. Wallinga-de; Boon, Kathy

doi:10.1007/bf02443872

Cited by 116 publications

(30 citation statements)

References 25 publications

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“…That view is supported by the elegant work of Gielen et al . [25], who completed four-electrode experiments in skeletal muscle preparations with 70 µm sensors separated from one another by 500 µm (1.5 mm span) and stimulated those preparations at 3 Hz to 1 MHz. With this separation, derived conductivities (inverse of resistivities) along ( σ L ) and across ( σ T ) fibers showed changes that included: 1) increasing σ L above 100 Hz, 2) decreasing σT between 1 and 10 kHz, and 3) phase shifts that ranged from ≈−20° to ≈+50° for specific frequencies and electrode orientations over the full range.…”

Section: Discussionmentioning

confidence: 99%

A New Approach for Resolution of Complex Tissue Impedance Spectra in Hearts

Pollard

Barr

2013

IEEE Trans. Biomed. Eng.

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This study was designed to test the feasibility of using sinusoidal approximation in combination with a new instrumentation approach to resolve complex impedance (uCI) spectra from heart preparations. To assess that feasibility, we applied stimuli in the 10–4000 Hz range and recorded potential differences (uPDs) in a four-electrode configuration that allowed identification of probe constants (Kp) during calibration that were in turn used to measure total tissue resistivity ρt from rabbit ventricular epicardium. Simultaneous acquisition of a signal proportional to the supplied current (Vstim) with uPD allowed identification of the V –I ratio needed for ρt measurement, as well as the phase shift from Vstim to uPD needed for uCI spectra resolution. Performance with components integrated to reduce noise in cardiac electrophysiologic experiments, in particular, and provide accurate electrometer-based measurements, in general, was first characterized in tests using passive loads. Load tests showed accurate uCI recovery with mean uPD SNRs between 101 and 103 measured with supplied currents as low as 10 nA. Comparable performance characteristics were identified during calibration of nine arrays built with 250 µm Ag/AgCl electrodes, with uCIs that matched analytic predictions and no apparent effect of frequency (F = 0.12, P = 0.99). The potential ability of parasitic capacitance in the presence of the electrode–electrolyte interface associated with the small sensors to influence the uCI spectra was therefore limited by the instrumentation. Resolution of uCI spectra in rabbit ventricle allowed measurement of ρt = 134 ± 53 Ω·cm. The rapid identification available with this strategy provides an opportunity for new interpretations of the uCI spectra to improve quantification of disease-, region-, tissue-, and species-dependent intercellular uncoupling in hearts.

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Section: Discussionmentioning

confidence: 99%

A New Approach for Resolution of Complex Tissue Impedance Spectra in Hearts

Pollard

Barr

2013

IEEE Trans. Biomed. Eng.

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“…When the signal carrier frequency was 1kHz to 300kHz, muscle’s electric conductivity in the parallel and the transverse directions gradually increased as the frequency rose; muscle tissue’s conductivity improved and signal diffused increasingly so as to make the signal not to be concentrated around the electrode effectively, while the signal quickly diffused throughout the entire muscle mass. The channel attenuation was supposed to reduced, however, muscle tissue’s electric characteristics highly differed in the parallel direction and the transverse direction [3], and signal diffuse speed also differed greatly in the two directions, thus, the measured channel attenuation was increased as the frequency ascended.…”

Section: Results and Analysismentioning

confidence: 99%

“…A large number of experiments showed [3, 4] that, different fibre growth characteristics in the parallel and the transverse directions caused large difference between electrical characteristics of the tissue in the two directions.…”

Section: Introductionmentioning

confidence: 99%

Path Loss Measurement and Channel Modeling with Muscular Tissue Characteristics

Qin

Zhang

Liu³

et al. 2017

TOBEJ

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Background:The galvanic coupling intra-body communication has low radiation and strong anti-interference ability, so it has many advantages in the wireless communication.Method:In order to analyze the effect of muscle tissue’s characteristics upon the communication channel, we selected the muscle of pig buttock as the experimental sample, and used it to study the attenuation property with the galvanic coupling intra-body communication channel along the parallel direction and the transverse direction relative to the muscular fibre line as well as on the surface of destroyed muscular fibre; the study frequency ranges from 1kHz to 10MHz.In the isotropic experiment, in order to destroy muscle’s fibre characteristics, we grinded the muscle four times, at least five minutes for each time. 0dbm sine-wave signal was input to measure the channel attenuation parameter S21 when the transmitter and the receiver were placed at different positions and different distances d1 and d2 (20mm, 40mm, 60mm), so as to analyze channel loss.Conclusion:Within the same frequency range and at the same communication distance, the maximum error of channel attenuation was 10dB; within the same frequency, as the communication distance was increased, the channel attenuation rose gradually, with 4dB increased every 20mm. The conclusion provides the basis for building the theoretical model in the future.

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“…The values of various parameters used in the simulations are listed in table 1. The values chosen for tissue electrical conductivity were based on the range of measured values in the literature [16][17][18][19][20][21][22][23][24][25]. At the outer boundary of computational domain, a zero spatial derivative of electric potential (i.e.…”

Section: Governing Equation and Numerical Methodsmentioning

confidence: 99%

“…Anisotropy in electrical conductivity of muscle tissue has been extensively investigated for the cardiac [16][17][18][19] and skeletal muscle [18,[20][21][22][23][24][25] suggesting a wider spectrum for skeletal than for a cardiac muscle (i.e. AR ¼ s L /s T ¼ 1.1-3.4 for cardiac and 2.7-15 for a skeletal muscle, table 1).…”

Section: Effect Of Anisotropic Electrical Conductivitymentioning

confidence: 99%

Impact of surrounding tissue on conductance measurement of coronary and peripheral lumen area

Choi

Jansen

Zhang

et al. 2012

J. R. Soc. Interface.

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Parallel conductance (electric current flow through surrounding tissue) is an important determinant of accurate measurements of arterial lumen diameter, using the conductance method. The present study is focused on the role of non-uniform geometrical/electrical configurations of surrounding tissue, which are a primary source of electric current leakage. Computational models were constructed to simulate the conductance catheter measurement with two different excitation electrodes spacings (i.e. 12 and 20 mm for coronary and peripheral sizing, respectively) for different vessel -tissue configurations: (i) blood vessel fully embedded in muscle tissue, (ii) blood vessel superficially embedded in muscle tissue, and (iii) blood vessel superficially embedded in muscle tissue with fat covering half of the arterial vessel (anterior portion). The simulations suggest that the parallel conductance and accuracy of measurement is dependent on the inhomogeneous/anisotropic configuration of surrounding tissue, including the asymmetric dimension and anisotropy in electrical conductivity of surrounding tissue. Specifically, the measurement was shown to be accurate as long as the vessel was superficial, regardless of the considerable total surrounding tissue dimension for coronary or peripheral arteries. Moreover, it was shown that the unfavourable impact of parallel conductance on the accuracy of conductance catheter measurement is decreased by the combination of a lower transverse electrical conductivity of surrounding muscle tissue, a smaller electrode spacing and a larger lumen diameter. The present findings confirm that the conductance catheter technique provides an accurate platform for sizing of clinically relevant (i.e. superficial and diseased) arteries.

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Electrical conductivity of skeletal muscle tissue: Experimental results from different musclesin vivo

Cited by 116 publications

References 25 publications

A New Approach for Resolution of Complex Tissue Impedance Spectra in Hearts

A New Approach for Resolution of Complex Tissue Impedance Spectra in Hearts

Path Loss Measurement and Channel Modeling with Muscular Tissue Characteristics

Impact of surrounding tissue on conductance measurement of coronary and peripheral lumen area

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