Electric-field induced strain in biological tissues

Doganay, Ozkan; Xu, Yuan

doi:10.1121/1.3501110

Cited by 11 publications

(14 citation statements)

References 15 publications

(12 reference statements)

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“…Both mechanical changes are determined by the fixed charged density in tissues. Since the changes in EIMC are mechanical in nature and they can be detected using ultrasound [36].…”

Section: Fixed Charge Density In Tissuesmentioning

confidence: 99%

Monitoring electric field induced changes in biological tissues and phantoms using ultrasound

Bhatt¹

2021

Preprint

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An external electric field can induce mechanical changes depending on the amplitude, frequency and duration of the applied electric field. This study is focused on monitoring the electric/electro-kinetic effects of real biological tissues (in vitro) and gelatin phantoms with high spatial resolution. In this study, we investigated the mean of the signal spectrum at the modulation frequency, root-mean-square of the noise in the spectrum, and signal-to-noise ratio (SNR) during the application of low-frequency AC electric field in tissues and phantoms. Our results show that the EIMC SNR can indicate the existence of AC electric current in samples, rather than be directly related to the sample's electro-kinetic properties of the samples. We also found that the SNR varies spatially even for homogenous samples. These two features might hinder the development of the proposed method to be a viable clinical diagnostic technique.

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“…Both mechanical changes are determined by the fixed charged density in tissues. Since the changes in EIMC are mechanical in nature and they can be detected using ultrasound [36].…”

Section: Fixed Charge Density In Tissuesmentioning

confidence: 99%

Monitoring electric field induced changes in biological tissues and phantoms using ultrasound

Bhatt¹

2021

Preprint

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“…Last but not the least I express my sincere thanks to my colleagues Krzysztof Wawrzyn, Barry Vuong and Carry Sun who have patiently extended all sorts of help for accomplishing this undertaking. [28], used to detect the electric-field induced mechanical changes (EIMC) in bulk tissues including deformation and strain. .........…”

Section: Acknowledgementsmentioning

confidence: 99%

Imaging the Electro-Kinetic Response of Biological Tissues with Optical Coherence Tomography

Demidov¹

2021

Preprint

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This thesis reports on developing a novel approach to imaging the electro-kinetic response of biological tissues with optical coherence tomography (OCT). The changes of backscattered OCT signal from tissues were investigated with a low frequency AC electric field being applied to the tissues. Advanced processing algorithms were developed to analyze the amplitude and phase changes of OCT signal. Two-dimensional electrically induced optical changes (EIOC) amplitude and phase images related to the electro-kinetic response of soft tissues were obtained with depth resolution and compared with structural OCT images. The procedure for removing the background noise from EIOC images was introduced.

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“…However, the mechanism of ESF effect on biological objects has not yet been fully understood. The reason may be that ESF induces various changes depending on exposure strength, duration, and other experimental conditions [Mcleod, 1992;Doganay and Xu, 2010]. In some reports, microscopic views of structural changes in the cells were illustrated, including changes in cell orientation [Methot et al, 2001], shape [Katnik and Waugh, 1990;Harutyunyan, 2015], cell migration [Erickson and Nuccitelli, 1984], and cell differentiation [Funk et al, 2009].…”

Section: Introductionmentioning

confidence: 99%

Effect of in vivo and in vitro exposure to electrostatic field on some hematological parameters in rats

Harutyunyan

Mkrtchyan

Sukiasyan

et al. 2016

Bioelectromagnetics

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The aim of this study was to investigate the effect of the external electrostatic field (ESF) on some hematological parameters in rats. Both in vivo and in vitro experiments were carried out. In in vivo investigations, rats were exposed to ESF (200 kV/m) during short (1 h) and long periods (6 days, 6 h daily). For in vitro study, the blood of intact rats was exposed to ESF for 1 h. Blood hematology was measured using validated ABX Micros ESV 60 Veterinary Hematology Analyzer. DNA damage in blood leucocytes was detected by means of comet assay. ESF effect on blood cell count was mainly manifested in white blood cells (WBC) and platelets. Damage of WBC was shown both in vitro and in vivo despite alterations in the count. This means the observed increase in WBC count in some cases might be a result of WBC compensatory mobilization from the bone marrow. Red blood cell (RBC) count and related parameters were slightly affected by ESF. Nevertheless, alterations in the shape and size of RBC were manifested. All ESF effects were extinguished in 14 days after the end of exposure. Bioelectromagnetics. 37:513-526, 2016. © 2016 Wiley Periodicals, Inc.

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Electric-field induced strain in biological tissues

Cited by 11 publications

References 15 publications

Monitoring electric field induced changes in biological tissues and phantoms using ultrasound

Monitoring electric field induced changes in biological tissues and phantoms using ultrasound

Imaging the Electro-Kinetic Response of Biological Tissues with Optical Coherence Tomography

Effect of in vivo and in vitro exposure to electrostatic field on some hematological parameters in rats

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