Ekspresja adiponektyny w otyłości trzewnej jest istotnym wyznacznikiem insulinooporności w otyłości olbrzymiej

Abstract

In severely obese patients, adiponectin gene expression in VAT is negatively correlated with serum levels of uric acid and is an independent determinant, together with anthropometric parameters of visceral obesity and serum adiponectin levels, of insulin resistance.

Endokrynne implikacje otyłości i zabiegów bariatrycznych

“…Recent evidence has demonstrated that there are over 50 different adipokines secreted from adipose tissue [48][49][50][51]. The main processes regulated by adipokines may be divided into three groups: 1. lipids and glucose metabolism; 2. inflammatory processes; and 3. blood pressure and haemostasis.…”

Circulating Chemerin Levels, Anthropometric Indices and Metabolic Profile in Morbid Obesity

“…It is worth mentioning that unlike other studies [22], we report higher values in the obese subjects. This finding could sustain that not circulating adiponectin, but the local expression in perivisceral fat and also the distribution of adipose tissue, are related with its metabolic functions [23,24]. An alternative explanation could be the adiponectin resistance phenomena, recently described by Engin [25], as a compensatory response caused by adiponectin unresponsiveness to IR at different stages of obesity.…”

Opioid-like peptides and ghrelin mitigation of bariatric results depends on obesity level

“…Obesity is connected with many changes of metabolic parameters. Qualification of patients for bariatric sur- gery must consider the lipid and carbohydrate panels and liver enzymes activity [16]. Analysis of triglycerides showed differences between the two groups of patients.…”