Eine neue Tetronsäure‐Synthese

A facile one‐pot synthesis of novel substituted 1,2,3,4‐tetrahydropyrimidine, part 2: Synthesis of 1‐(aralkyl/aryl)‐3‐(alkyl/aralkyl/aryl)‐5‐aroyl‐1,2,3,4‐tetrahydropyrimidines

“…Starting materials 1a-c [1], 3b [4], 3c [5], 3h [5], 3e [6], 3f [6], 3g [7] were prepared by reported procedures. The unknown starting materials 3a, 3d, 3i and 3j were prepared by the reported procedures [6,7] and their analytical and spectral data are given below.…”

Developments in the Synthesis of 3-Acyltetramic Acid Natural Products

“…The synthetic methodology for 3-acyltetramic acids has been evolved by applying well-established synthetic methods for accessing structurally related 3-acyltetronic acids and 3-acylthiotetronic acids [43][44][45][46][47][48]. Markopoulou et al have demonstrated successful application of a method reported by Benary for 3-acylthiotetronic acids [43] as the one for 3-acyltetramic acids.…”

A Facile One‐Pot Synthesis of Tetrahydropyrimidines. Part 3. Synthesis of [Alkanediylbis(3‐alkyl/aralkyl/aryl‐3,6‐dihydropyrimidine‐1,5 (2H)‐diyl)]bis(arylmethanones) and [1,4‐Phenylenebis(3‐phenyl‐3,6‐dihydropyrimidine‐1,5(2H)‐diyl)] bis(phenylmethanone).

“…The starting materials 1a [5], 1b [6], 1c [7] and 1e-f [8] were prepared by reported procedures. The unknown starting material 1d was prepared by reported procedure [8] and its analytical and spectral data are given below.…”