Eikenella Corrodens and Intrauterine Contraceptive Device

Drouet, Emmanuel; Montclos, H. De; Boude, M; Denoyel, G. A.

doi:10.1016/s0140-6736(87)91517-0

Cited by 13 publications

(8 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…respectively; lanes 6 and 7 strains isolated from a patient's blood and lung abscess, respectively diverse disease spectrum of Eikenella corrodens infections than previous reports [3,[5][6][7][8][9][10][11][12][13][14][15][16][17]. Our experience showed a more Lane M DNA size markers and molecular sizes, indicated in kilobase (kb) pairs.…”

Section: Discussionmentioning

confidence: 58%

“…Eikenella corrodens is part of the commensal flora of the oral cavity and is also an inhabitant of the mucosal surface of the gastrointestinal and genitourinary tracts [4]. It may cause a variety of infections [5][6][7][8][9][10][11][12][13][14][15][16][17] that, in most reported cases, appear to be indolent and benign [3]. However, there have been sporadic reports on the spectrum of invasive infections due to this organism.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Features of Patients with Invasive Eikenella corrodens Infections and Microbiological Characteristics of the Causative Isolates

Sheng

Hsueh

Hung

et al. 2001

EJCMID

View full text Add to dashboard Cite

Clinical features of 43 cases of invasive Eikenella corrodens infections diagnosed at National Taiwan University Hospital during a 6-year period (1993-1998) were analyzed. The clinical syndromes included head and neck infection (56%), pulmonary infection (23%), intra-abdominal infection (14%), cutaneous infection (5%), skeletal infection (2%), endocarditis (2%), and pelvic abscess (2%). Nearly two-thirds of the patients (63%) had pre-existing diseases. Malignancy (35%), especially of the head and neck, was the most common underlying illness. More than half of the patients (56%) had associated factors predisposing to invasive Eikenella corrodens infection. Polymicrobial infections occurred in 28 (65%) patients, with two-thirds of the concurrent isolates being streptococci (66%). Five cases were fatal, with four deaths directly attributable to invasive Eikenella corrodens infection. Antimicrobial susceptibility testing and molecular typing were performed on 23 preserved Eikenella corrodens isolates. Antimicrobial susceptibility testing showed that Eikenella corrodens isolates were susceptible to penicillin, amoxicillin, cefoxitin, cefotaxime, cefepime, ciprofloxacin, and imipenem. The isolates were resistant to clindamycin, metronidazole, cephalothin, and cefuroxime. None of the 23 isolates produced beta-lactamase. Random amplified polymorphic DNA patterns of the 23 isolates were different, suggesting that different clones of Eikenella corrodens caused these infections.

show abstract

Section: Discussionmentioning

confidence: 58%

Section: Introductionmentioning

confidence: 99%

Clinical Features of Patients with Invasive Eikenella corrodens Infections and Microbiological Characteristics of the Causative Isolates

Sheng

Hsueh

Hung

et al. 2001

EJCMID

View full text Add to dashboard Cite

show abstract

“…Eikenella corrodens is a facultative gram-negative bacillus commonly found in the oral cavity (4, 9) and in the intestinal and genital tracts (7,23). This organism is considered a candidate periodontal pathogen based on various clinical studies showing that elevated numbers of this species are associated with periodontitis (13,17,22).…”

mentioning

confidence: 99%

Restriction endonuclease analysis of Eikenella corrodens

et al. 1990

View full text Add to dashboard Cite

Eikenella corrodens is a gram-negative facultative bacillus commonly found in the oral cavity. Although the role of E. corrodens in periodontitis is not clear, its isolation from extraoral infections attests to its pathogenic potential. Previous studies suggested that this species is phenotypically diverse. In the present study, we used restriction endonuclease analysis (REA) to assess the genetic diversity of this species and to explore the applicability of REA in studying the transmission of E. corrodens. Two groups of E. corrodens isolates were used in this study. Group 1 included 47 epidemiologically independent isolates recovered from dental plaques in periodontally healthy subjects and periodontitis patients and from extraoral infections in different geographic areas. Group 2 E. corrodens included 40 isolates recovered from two periodontitis patients and two periodontally healthy subjects. The results indicated that E. corrodens is genetically heterogeneous, as determined by REA. The majority of the group 1 E. corrodens isolates exhibited strain-specific restriction patterns. Forty restriction patterns were distinguishable among the 47 isolates. Analyses of group 2 isolates revealed that three of four subjects harbored more than one clonal type of E. corrodens. In one instance, a periodontitis patient was found to be colonized by six different clones. Furthermore, two different clonal types of E. corrodens were recovered from a single periodontal pocket in this patient. The results indicated that REA may be a useful tool in the epidemiologic investigation of E. corrodens infections.

show abstract

“…However, despite appropriate and indolent, invasive and recurrent infections, such perirenal abscesses, vertebral osteomyelitis or endocarditis have been reported; [4][5][6]. Gynaecological infections such as chorioamnionitis or tubo-ovarian abscesses caused by E. corrodens are rare, but these have been described mostly in women using IUD [7][8][9]. This fastidious, slow-growing bacteria frequently causes polymicrobial infections and may be underdiagnosed as it is frequently outgrown by coinfecting microorganisms in standard culture media [2,9].…”

Section: Sirmentioning

confidence: 99%