Bacteremia caused by Eikenella corrodens in a patient with pelvic inflammatory disease

BACKGROUND The bacterium Eikenella , classified as a gram-negative member of the phylum Proteobacteria, is distinguished by its rarity, corrosive nature, facultative anaerobic properties, and conditional pathogenicity. It represents the sole species within its genus-Eikenella corrodens (E. corrodens )-and can be found colonizing both human and animal oral and nasopharyngeal regions. Additionally, it occasionally inhabits the gastrointestinal or urogenital tracts. However, its slow growth rate can be attributed to its high nutritional requirements. However, there is an uneven distribution of construction and diagnostic capacity in China which poses undeniable challenges for the clinical examination and analysis of this case, especially in the basic hospitals. CASE SUMMARY Here we presented a case of empyema associated with E. corrodens infection in a 67-year-old male patient without any previous history of infectious diseases in our primary hospital in Dongguan district of China. The patient was admitted due to recurrent worsening cough, sputum production, and dyspnea for 3 d, which had persisted for over 20 years. Moreover, the patient experienced a one-hour episode of unconsciousness. Upon admission, immediate comprehensive examinations were conducted on the patient which subsequently led to his admission to the intensive care unit. Meanwhile, the patient presented with drowsiness and profuse sweating along with bilateral conjunctival edema observed during initiation of non-invasive ventilation, suggesting empyema. A significant amount of coffee-colored malodorous pleural fluid was drained during the procedure above and sent to the laboratory department for inspection. Finally, laboratory culture results confirmed the presence of E. corrodens infection in the pleural fluid sample. The patient received antimicrobial therapy until died on day 22 in the hospital. CONCLUSION In this report, we presented a case of empyema associated with E. corrodens infection. Multiple courses of morphological examination, viable culture analysis, and biochemical identification revealed its difficulties in detecting distinctive characteristics, as well as a detection model worth promoting. It’s just that there were still certain deficiencies in terms of morphological assessment, biochemical identification, and drug susceptibility testing.

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Morphological and molecular identification of a new local strain of Eikenella corrodens isolated from chronic periodontitis

Salih,

Al-Rawi

2023

Medicinski časopis

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Objectives. This research focused on the morphological and molecular identification of a new local strain of Eikenella corrodens, which was isolated from 25 cases infected with chronic periodontitis. Methods. A modified Todd Hewitt agar medium was used for the first time locally to isolate the strain. The researchers then examined the isolate to determine its ability for slime layer production and formation of biofilm. Results. The results of the culture revealed that only one out of the twenty-five cases tested positive for Eikenella corrodens, accounting for a 4% occurrence. This positive result was further confirmed by PCR and gel electrophoresis. To identify the strain, the sequence of the 16S rRNA gene of Eikenella corrodens was determined and compared with the existing data available at the National Center for Biotechnology Information (NCBI). The sequence was deposited in GenBank under the accession number OQ996282.1. The strain was named MeAm. Additionally, the researchers found that this particular isolate demonstrated a strong ability to form biofilm. Conclusion. These findings contribute to the understanding of the local strain of Eikenella corrodens and its characteristics concerning chronic periodontitis, providing valuable insights for further research and potential treatment strategies.

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Bacteremia caused by Eikenella corrodens in a patient with pelvic inflammatory disease

Cited by 3 publications

References 16 publications

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Eikenella corrodens isolated from pleural effusion: A case report

Morphological and molecular identification of a new local strain of Eikenella corrodens isolated from chronic periodontitis

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