Egg yolk antibody combined with bismuth-based quadruple therapy in Helicobacter pylori infection rescue treatment: a single-center, randomized, controlled study

Cheng, Sha; Li, Huan; Luo, Ju; Chi, Jingshu; Zhao, Wenfang; Lin, Jiahui; Xu, Canxia

doi:10.3389/fmicb.2023.1150129

Cited by 3 publications

(1 citation statement)

References 40 publications

(50 reference statements)

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“…After 4 weeks from the end of the treatment, H. pylori eradication, assessed through urea breath tests and the Global Overall Symptom Scale (GOS), indicated that both the case and control groups achieved satisfactory eradication rates. However, it is noteworthy that IgY‐ H. pylori effectively reduced disease symptoms and had fewer side effects 36 …”

Section: Resultsmentioning

confidence: 99%

Oral immunotherapy for Helicobacter pylori: Can it be trusted? A systematic review

Peypar,

Yeganeh,

Ramazani

et al. 2024

Helicobacter

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BackgroundHelicobacter pylori (H. pylori) is a rod‐shaped, gram‐negative, microaerophilic bacterium that can be identified by gram staining. Its relationship with cancer is significant since it is involved in approximately 80% of gastric cancers and 5.5% of all malignant cancers. Two lines of treatment have been defined for H. pylori, but almost 40% of patients do not respond to the first line. Recent trials have investigated oral Immunotherapy as a new treatment method. The aim of this systematic review was to investigate the potential effects of oral Immunotherapy on eradication rate of H. pylori in human studies.MethodsThe systematic review was performed according to PRISMA guidelines. We searched online databases, including Scopus, PubMed, and Web of Science (ISI). Our search strategy was limited to English articles and studies on human populations that use oral immunotherapy for H. pylori.ResultsThe total number of primary research records in different databases was 2775. After removing duplicate articles (n = 870), we excluded 1829 for reasons including non‐human studies, irrelevance to our study objective, non‐English language, or lack of information. Of the remaining 76 articles, only seven had sufficient information, and the rest were excluded. The studies were divided into two groups: those that used bovine antibody and those that used immunoglobulin Y to eradicate H. pylori.ConclusionIn the group of Immunoglobulin Y, three out of four studies suggest that using Immunoglobulin Y for the treatment of H. pylori infection is significant. However, the group using bovine antibody for the treatment of H. pylori infection has various results, as two out of three studies concluded that bovine antibody therapy is not significant.

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Section: Resultsmentioning

confidence: 99%

Oral immunotherapy for Helicobacter pylori: Can it be trusted? A systematic review

Peypar,

Yeganeh,

Ramazani

et al. 2024

Helicobacter

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Sodium sulfite-driven Helicobacter pylori eradication: Unraveling oxygen dynamics through multi-omics investigation

Huang,

Liu,

Huang

et al. 2024

Biochemical Pharmacology

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Recent trends in Helicobacter pylori management: harnessing the power of AI and other advanced approaches

Addissouky,

Wang,

El Sayed

et al. 2023

Beni-Suef Univ J Basic Appl Sci

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Background Helicobacter pylori (H. pylori) is a bacterial infection that is prevalent and affects more than half of the world's population, causing stomach disorders such as gastritis, peptic ulcer disease, and gastric cancer. Main body The diagnosis of H. pylori infection relies on invasive and non-invasive techniques emerging artificial intelligence, and antibiotic therapy is available, but antibiotic resistance is a growing concern. The development of a vaccine is crucial in preventing H. pylori-associated diseases, but it faces challenges due to the bacterium's variability and immune escape mechanisms. Despite the challenges, ongoing research into H. pylori's virulence factors and immune escape mechanisms, as well as the development of potential vaccine targets, provides hope for more effective management and prevention of H. pylori-associated diseases. Recent research on H. pylori's immune escape mechanisms and novel immune checkpoint inhibitors could also lead to biomarkers for early cancer detection. Therefore, experts have suggested a combination of traditional and herbal medicine with artificial intelligence to potentially eradicate H. pylori. Short conclusion H. pylori infection remains a significant global health problem, but ongoing research into its properties and advanced technologies in addition to the combination of traditional and herbal medicine with artificial intelligence may also lead to the eradication of H. pylori-associated diseases. Graphical abstract

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Egg yolk antibody combined with bismuth-based quadruple therapy in Helicobacter pylori infection rescue treatment: a single-center, randomized, controlled study

Cited by 3 publications

References 40 publications

Oral immunotherapy for Helicobacter pylori: Can it be trusted? A systematic review

Oral immunotherapy for Helicobacter pylori: Can it be trusted? A systematic review

Sodium sulfite-driven Helicobacter pylori eradication: Unraveling oxygen dynamics through multi-omics investigation

Recent trends in Helicobacter pylori management: harnessing the power of AI and other advanced approaches

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