Ege Üniversitesi Hastanesi'ne başvuran santral sinir sistemi enfeksiyonu olgularında saptanan viral etkenler

Abstract

Amaç: Santral sinir sistemi enfeksiyonları, hızlı ilerleme potansiyeli ve kalıcı nörolojik hasar olasılığı nedeniyle çoğunlukla acil tanı ve tedavi yaklaşımı gerektirir. Bu çalışmada Ege Üniversitesi Tıp Fakültesi Tıbbi Mikrobiyoloji Anabilim Dalı'na viral santral sinir sistemi enfeksiyonu ön tanısı düşünülerek gönderilen beyin omurilik sıvısı (BOS) örneklerinde nükleik asit testleri ile saptanan viral etkenlerin değerlendirilmesi amaçlandı. Gereç ve Summary Aim: Central Nervous system (CNS) infections require a rapid diagnosis and treatment approach due to their potential of rapid progression and the possibility of permanent neurological damage. In this study, viral agents detected by nucleic acid tests in the cerebrospinal fluid samples of patients with a suspicion of viral CNS infection were sent to Medical Microbiology Laboratory of Ege University Hospital and evaluated. Materials and Methods:

Menejit Ön tanısıyla Başvuran Hastalarda Beyin Omirilik Sıvı Sonuçlarının Değerlendirilmesi

“…In the study conducted by Sarinoglu et al (24) in 2016, HSV-1 was the most detected factor in 12 (34.2%) patients, followed by Enterovirus detected in 8 (22.8%) patients. In the study of Soylar et al (7), EBV had the highest percentage with a rate of 15% among viral agents. In the study of Çaycı et al (25), the most common virus was HSV-1 (20%) and the most common bacterial agent was Streptococcus pneumoniae (40%).…”

“…The most important advantage of PCR against bacterial culture is its high sensitivity, fast results and no need for live bacteria. For this reason, it has been the most frequently used method in recent years (6,7). There may be a change in the profile of the agents of meningitis with the new vaccines that have been routinely applied in recent years (8).…”