“…It is an amphoteric material which shows hydrophilic characteristics [24,25]. Thus CMCh has several advantages over chitosan, such as increased water solubility, better biocompatibility, high moisture retention ability, excellent biodegradability [26], improved antioxidant property [27], as well as, enhanced antibacterial activity [28]. The preparation of O-CMCh is achieved simply by reacting chitosan with monochloroacetic acid in alkaline medium [29].…”