Efficient kefiran production by Lactobacillus kefiranofaciens ATCC 43761 in submerged cultivation: Influence of osmotic stress and nonionic surfactants, and potential bioactivities

Dailin, Daniel Joe; Elsayed, Elsayed A.; Malek, Roslinda Abd; Hanapi, Siti Zulaiha; Selvamani, Shanmugaprakasham; Ramli, Solleh; Sukmawati, Dalia; Sayyed, R. Z.; Enshasy, Hesham Ali El

doi:10.1016/j.arabjc.2020.09.030

Cited by 15 publications

(7 citation statements)

References 54 publications

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“… Thanomsub et al (2007) reported rhamnolipid A and B having anti-proliferative activity against human breast cancer cell line and insect cell line C6/36 with a minimum inhibitory concentration of 6.25 μg/mL and 50 μg/mL, respectively. A water soluble polysaccharide kefiran produced by Lactobacillus kefiranofaciens ATCC 43761 showed anticancer activity with 193.89 μg/mL of IC 50 against breast cancer (MCF-7) cells ( Dailin et al, 2020 ). These properties make biosurfactants a suitable applicant for biomedical preparations.…”

Section: Applications Of Biosurfactantsmentioning

confidence: 99%

Microbial surfactants: A journey from fundamentals to recent advances

et al. 2022

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Microbial surfactants are amphiphilic surface-active substances aid to reduce surface and interfacial tensions by accumulating between two fluid phases. They can be generically classified as low or high molecular weight biosurfactants based on their molecular weight, whilst overall chemical makeup determines whether they are neutral or anionic molecules. They demonstrate a variety of fundamental characteristics, including the lowering of surface tension, emulsification, adsorption, micelle formation, etc. Microbial genera like Bacillus spp., Pseudomonas spp., Candida spp., and Pseudozyma spp. are studied extensively for their production. The type of biosurfactant produced is reliant on the substrate utilized and the pathway pursued by the generating microorganisms. Some advantages of biosurfactants over synthetic surfactants comprise biodegradability, low toxicity, bioavailability, specificity of action, structural diversity, and effectiveness in harsh environments. Biosurfactants are physiologically crucial molecules for producing microorganisms which help the cells to grasp substrates in adverse conditions and also have antimicrobial, anti-adhesive, and antioxidant properties. Biosurfactants are in high demand as a potential product in industries like petroleum, cosmetics, detergents, agriculture, medicine, and food due to their beneficial properties. Biosurfactants are the significant natural biodegradable substances employed to replace the chemical surfactants on a global scale in order to make a cleaner and more sustainable environment.

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Section: Applications Of Biosurfactantsmentioning

confidence: 99%

Microbial surfactants: A journey from fundamentals to recent advances

et al. 2022

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“…This EPS can be found in the pure culture of Lactobacillus kefiranofaciens ( L. kefiranofaciens ) or in kefir grains under aerobic environments and in the mixed cultures of Saccharomyces cerevisiae with L. kefiranofaciens under anaerobic environments [ 118 , 119 , 120 , 121 ]. Compared to other polysaccharides of microbial origin, kefiran’s main advantage is that it is produced from LAB, generally recognized as safe [ 122 , 123 ].…”

Section: Types and Properties Of Bacterial Exopolysaccharidesmentioning

confidence: 99%

“…It has been shown that lactose is the best carbon source for kefiran production [ 124 , 125 ]. The highest output of kefiran has been acquired in the temperature range of 20–30 °C and pH values between 5 and 6 [ 118 , 126 , 127 , 128 ].…”

Section: Types and Properties Of Bacterial Exopolysaccharidesmentioning

confidence: 99%

Biomedical Applications of Bacterial Exopolysaccharides: A Review

et al. 2021

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Bacterial exopolysaccharides (EPSs) are an essential group of compounds secreted by bacteria. These versatile EPSs are utilized individually or in combination with different materials for a broad range of biomedical field functions. The various applications can be explained by the vast number of derivatives with useful properties that can be controlled. This review offers insight on the current research trend of nine commonly used EPSs, their biosynthesis pathways, their characteristics, and the biomedical applications of these relevant bioproducts.

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“…Con el mismo interés de elevar la producción del EPS, se probó la aplicación de estrés osmótico. Los resultados indican que al someter la producción de kefiran a un estrés de 550 mOsmol.kg-1 y 1.0 g.L-1 de Triton X-100 al tiempo 0, se obtiene un rendimiento mayor al 72.9%, con respecto a la producción normal (Dailin et al, 2020). El aumento se explica por la acumulación de solutos en el citoplasma de las células bacterianas, asegurando así una mayor presión interna de solutos y un flujo continuo de moléculas de agua hacia el interior celular (Le Marrec, 2011).…”

Section: Kefiran: Exopolisacárido (Eps) Del Kéfirunclassified

Biotecnología del kéfir: una revisión sobre las aplicaciones y sus perspectivas futuras

Vázquez

Koch

2021

ACI

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El kéfir ha sido ampliamente utilizado a lo largo de la historia de la humanidad y tiene siglos de legado. Actualmente, sus aplicaciones están directamente relacionadas con la salud del ser humano y además se han desarrollado polímeros cuyas aplicaciones continúan en investigación. Este artículo de revisión pretende realizar un viaje entre sus aplicaciones y las perspectivas futuras. En los últimos decenios, las demandas de los consumidores en el ámbito de la producción de alimentos han cambiado considerablemente. Los consumidores creen cada vez más que los alimentos contribuyen directamente a su salud. Hoy en día, los alimentos no sólo están destinados a satisfacer el hambre y a proporcionar los nutrientes necesarios, sino también a prevenir las enfermedades relacionadas con la nutrición y a mejorar el bienestar físico y mental. A este respecto, los alimentos funcionales desempeñan un papel destacado; su demanda creciente puede explicarse por el costo cada vez mayor de la atención sanitaria, el aumento constante de la esperanza de vida y el deseo de las personas mayores de mejorar la calidad de sus últimos años. La gran aceptación de los consumidores, los elevados gastos en salud, la necesidad de mejorar la calidad de vida, retrasar el proceso de envejecimiento, el crecimiento industrial y el desarrollo de nuevos productos hacen del kéfir un producto de alto interés.

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Efficient kefiran production by Lactobacillus kefiranofaciens ATCC 43761 in submerged cultivation: Influence of osmotic stress and nonionic surfactants, and potential bioactivities

Cited by 15 publications

References 54 publications

Microbial surfactants: A journey from fundamentals to recent advances

Microbial surfactants: A journey from fundamentals to recent advances

Biomedical Applications of Bacterial Exopolysaccharides: A Review

Biotecnología del kéfir: una revisión sobre las aplicaciones y sus perspectivas futuras

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