Abstract:We have recently (1) introduced an exact mathematical description of chain molecules based on discrete analogues of the curvature and torsion concepts in differential geometry called the kappa-tau framework, and applied it to the analysis of all known protein structures. We here use it to extract and analyze defined structural motifs from the Protein Data Bank. We find a class of left handed 4 residues long, open turns, tentatively called left alpha-tums, which do not exhibit internal backbone H-bonding and jo… Show more
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