Conventional cloud server dual end vulnerability detection methods mainly use P2P (peer-to-peer) structure to generate dual end vulnerability detection programs, which are vulnerable to the dual identities of the server and the client, resulting in relatively high vulnerability detection errors. Therefore, a new cloud server dual end vulnerability detection method needs to be designed based on heuristic genetic algorithm. That is to say, the heuristic genetic algorithm is used to build a cloud server dual end vulnerability detection model, and the cloud server dual end vulnerability detection middleware is designed, thus realizing the cloud server dual end vulnerability detection. The experimental results show that the designed dual end vulnerability detection method for cloud server based on heuristic genetic algorithm has low relative error of vulnerability detection, which proves that the designed vulnerability detection method has good detection effect, reliability, and certain application value, and has made certain contributions to improving the security of cloud server operation.