Efficacy of ultrasound-guided core needle gun biopsy in diagnosing cervical lymphadenopathy

Oh, Kyoung Ho; Woo, Jeong-Soo; Cho, Jae-Gu; Baek, Seung Kuk; Jung, Kwang‐Yoon; Kwon, Soon Young

doi:10.1016/j.anorl.2016.01.013

Cited by 38 publications

(34 citation statements)

References 19 publications

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“…Fourth, there were few false-positive and false-negative results on PET/CT. Lastly, there was no case of surgical excisional biopsy, which may affect the results even though US-guided tissue sampling is a well-known first-line investigation of choice that is safe, cost effective, and fast with a high diagnostic efficacy in cervical LNs [28][29][30]. We expect that further studies with larger sample sizes and various targeted patients will validate our results in the near future.…”

Section: Discussionmentioning

confidence: 62%

Cervical Lymph Nodes Detected by F-18 FDG PET/CT in Oncology Patients: Added Value of Subsequent Ultrasonography for Determining Nodal Metastasis

et al. 2019

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Background and Objectives: To investigate the diagnostic performance of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) and subsequent ultrasonography (US) for determining cervical nodal metastasis in oncology patients. Materials and Methods: Fifty-nine cervical lymph nodes (LNs) initially detected by PET/CT with subsequent neck US were included in this retrospective study. All LNs were subjected to US-guided fine-needle aspiration or core needle biopsy. The maximum standardized uptake value (SUVmax) and sonographic features were assessed. Results: Forty-three of 59 cervical LNs detected by PET/CT were malignant. PET/CT alone showed a highest diagnostic value for metastatic LNs with 81.4% sensitivity, 68.8% specificity, and 78% accuracy when SUVmax ≥5.8 was applied as an optimal cut-off value. Combined PET/CT and subsequent US diagnoses for determining nodal metastasis showed the following diagnostic performance: 81.4% sensitivity, 87.5% specificity, and 83.1% accuracy. There was a significant difference in the diagnostic performance between the two diagnostic imaging approaches (p = 0.006). Conclusions: Combined diagnosis using subsequent US showed a significantly higher diagnostic performance for determining nodal metastasis in the neck. Therefore, we believe that our proposed diagnostic strategy using subsequent US can be helpful in evaluating cervical LNs on PET/CT. Moreover, our results clarify the need for US-guided tissue sampling in oncology patients.

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Section: Discussionmentioning

confidence: 62%

Cervical Lymph Nodes Detected by F-18 FDG PET/CT in Oncology Patients: Added Value of Subsequent Ultrasonography for Determining Nodal Metastasis

et al. 2019

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“…The authors suggest diagnostic lymphadenectomy as a second line diagnostic evaluation after two negative FNACs . In contrast, recent articles demonstrated low FNAC sensitivity rates (11%), particularly in lymphoma . Subclassification of lymphoma was possible in only 66% of patients .…”

Section: Discussionmentioning

confidence: 99%

“…In our view, FNAC in terms of sensitivity and time effort is not an alternative to surgical lymphadenectomy, and has, therefore, not be employed in this study. Sensitivity rates, especially for lymphoma, might be higher (up to 88%) for core needle gun biopsy . As this technique is not state of the art and tumor seeding might occur, this technique was not applied in our study.…”

Section: Discussionmentioning

confidence: 99%

Sonographic differentiation between lymphatic and metastatic diseases in cervical lymphadenopathy

et al. 2017

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“…Many different conditions may cause cervical lymphadenopathy (LAP), such as viral or bacterial i n f e c t i o n s , t u b e r c u l o s i s , toxoplasmosis, cat-scratch disease, Kikuchi's disease, collagen vascular disease and neoplasia. 1 However, the most common causes of LAP are inflammatory and reactive conditions, only a small proportion has serious pathology, such as malignancy. 2 Against this small proportion, many parents may be excessively worried about to enlarged lymph node, because of this association.…”

Section: Introductionmentioning

confidence: 99%

Differentiation of benign from malignant cervical lymphadenopathy by ultrasonography in children

2020

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Introduction. The most common causes of cervical lymphadenopathy (LAP) are inflammatory and reactive conditions; only a small proportion have serious pathology, such as malignancy. The objective of this study was to evaluate the relationship between USG findings and histopathological diagnosis of the cervical LAP. Population and Methods. This retrospective study comprised the cases of cervical LAP in patients aged under 20 years old followed in our center between January 2007 to December 2016. Based on pathology reports, we divided the patients into two groups: benign and malignant. Pathology results and USG findings were compared. Results. After the analyze of the histopathological results and USG findings, 107 patients with persistent cervical LAP (44 malignant; 63 benign) were included in the study. Mean age of malignant and benign group were 14 ± 6.1; 11.9 ± 4.8 years, respectively. Hilar vascularity for benign LAP was highly statistically significant (P < 0.0001) and peripheral flow and mixed vascularity for malignant LAP were also statistically significant (p < 0.05). There was not a significant difference in the maximum diameter (27.3 ± 11.1 mm and 29.8 ± 12.3 mm, respectively), however, there was a significant difference in the minimum diameter between benign and malignant groups (13.7 ± 7.3 mm and 18.7 ± 8.8 mm, respectively). Conclusions. The present study suggests that there is a relationship between US and biopsy findings for the differentiation of benign from malignant LAP, especially in terms of nodal hilus and intranodal vascular pattern.

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Efficacy of ultrasound-guided core needle gun biopsy in diagnosing cervical lymphadenopathy

Abstract: The US-CNB is safe, effective, and has a high diagnostic yield for cervical lymphadenopathy. The US-CNB may also be useful for diagnosing lymphoma and Kikuchi's disease.

Cited by 38 publications

References 19 publications

Cervical Lymph Nodes Detected by F-18 FDG PET/CT in Oncology Patients: Added Value of Subsequent Ultrasonography for Determining Nodal Metastasis

Cervical Lymph Nodes Detected by F-18 FDG PET/CT in Oncology Patients: Added Value of Subsequent Ultrasonography for Determining Nodal Metastasis

Sonographic differentiation between lymphatic and metastatic diseases in cervical lymphadenopathy

Differentiation of benign from malignant cervical lymphadenopathy by ultrasonography in children

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