Efficacy of superficial cryotherapy on the eyebrows of patients with alopecia universalis also treated with contact immunotherapy on the scalp: a prospective, split‐face comparative study

Choe, Sung Jay; Lee, Won‐Soo

doi:10.1111/ijd.13533

Cited by 7 publications

(4 citation statements)

References 14 publications

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“…The treatment was most effective when performed at the interval of 2 weeks or less . In a recent half‐head study, superficial cryotherapy was reported to significantly increase hair thickness and density of eyebrows compared with control . The effects of this treatment are expected to be comparable with the treatments above without severe complication.…”

Section: Second‐line Therapiesmentioning

confidence: 99%

Management of alopecia areata: Updates and algorithmic approach

Lee

2017

The Journal of Dermatology

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Alopecia areata is a chronic, recurrent and non-scarring alopecia. The prognoses of patients are very diverse. The larger the area of hair loss, the poorer the treatment response and greater the probability of chronic disease progression. Numerous treatments have been introduced, but curative treatments have yet to be established. The long-term efficacy of the current treatments is minimal, and the therapeutic response varies widely. Recent clinical trials have attempted to apply therapeutic metrics, such as the Severity of Alopecia Tool, and many have been designed as randomized controlled studies, enabling a more precise evaluation of existing treatments. There have been updates in practice, efficacy or indications of therapeutics that have been previously used. Moreover, the use of novel treatments such as biologics has recently been introduced. Commonly, the most important factor in determining the treatment modality for alopecia areata has been the extent of hair loss. However, if the disease activity is high and likely to progress, combination therapy with adjuvant modalities will be more desirable. This review will discuss the therapeutic effects of existing and newly-introduced treatments based on their quantity, quality of evidence and expected complications. In addition, an algorithmic approach to management of alopecia areata is proposed according to clinical subtype, severity, onset and activity of the disease.

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Section: Second‐line Therapiesmentioning

confidence: 99%

Management of alopecia areata: Updates and algorithmic approach

Lee

2017

The Journal of Dermatology

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“…In another study, 11 patients with recalcitrant AA to various treatments for 6 months responded to cryotherapy after 5 weeks of treatment 146 . Although cryotherapy appears to have therapeutic potential 17 145 146 147 148 149 150 151 152 153 154 155 more studies are needed to prove its effectiveness.…”

Section: Resultsmentioning

confidence: 99%

Guidelines for the Management of Patients with Alopecia Areata in Korea: Part I Topical and Device-based Treatment

et al. 2023

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Background Alopecia areata (AA) is a chronic disease with an unpredictable disease course and severe psychological impact. Objective To provide evidence- and consensus-based insights regarding the treatment of patients with AA in Korea. Methods We searched for relevant studies on the topical and device-based treatment of AA in the literature from inception until May 2021. Evidence-based recommendations were also prepared. The evidence for each statement was graded and classified according to the strength of the recommendations. Hair experts from the Korean Hair Research Society (KHRS) voted on the statements, and an agreement of 75% or greater was considered as consensus. Results Currently, there remains a scarcity of topical treatments, which is supported by robust evidence from a number of high-quality randomized controlled trials. Current evidence supports the efficacy of topical corticosteroids, corticosteroid intralesional injection, and contact immunotherapy in AA patients. Topical corticosteroids and contact immunotherapy are recommended for pediatric AA. A consensus was achieved in 6 out of 14 (42.8%), and 1 out of 5 (20.0%) statements pertaining to topical and device-based treatments in AA, respectively. The expert consensus was from a single country, and the study may not cover all the treatments used. Conclusion The present study provides up-to-date, evidence-based treatment guidelines for AA based on the consensus reached among experts after considering regional healthcare circumstances, adding diversity to the previous guidelines.

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“…Although cryotherapy is less effective than topical and intralesional steroids, it has been an effective adjuvant modality along with topical steroids and contact immunotherapy for multiple patches and eyebrow lesions, respectively. [ 55 56 57 ]…”

Section: Resultsmentioning

confidence: 99%

IADVL SIG pediatric dermatology (Academy) recommendations on childhood alopecia areata

Katakam

Behera

Ranugha

et al. 2022

Indian Dermatol Online J

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Alopecia areata (AA) is a chronic inflammatory disease characterized by nonscarring alopecia. In contrast to adult onset AA, the epidemiology, clinical characteristics, and therapy of childhood AA are less explored. This study aims at providing recommendations for the management of childhood AA. The special interest group (SIG) in pediatric dermatology under the Indian Association of Dermatology, Venereology and Leprosy (IADVL) conducted online meetings from February 2021 to September 2021, intending to identify the critical aspects in the diagnosis and treatment of AA. The classification, diagnosis, and tools for assessment of disease activity of childhood AA have been described in this study, along with recommendations for topical and systemic therapy, including newer therapeutic options.

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Efficacy of superficial cryotherapy on the eyebrows of patients with alopecia universalis also treated with contact immunotherapy on the scalp: a prospective, split‐face comparative study

Abstract: Superficial cryotherapy is associated with minimal to no adverse events and exhibits high compliance and relatively good efficacy. Thus, this treatment is an important additional option for patients with AA of the eyebrow.

Cited by 7 publications

References 14 publications

Management of alopecia areata: Updates and algorithmic approach

Management of alopecia areata: Updates and algorithmic approach

Guidelines for the Management of Patients with Alopecia Areata in Korea: Part I Topical and Device-based Treatment

IADVL SIG pediatric dermatology (Academy) recommendations on childhood alopecia areata

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