Efficacy of superb microvascular imaging of ultrasound for diagnosis of gallbladder lesion

Abstract

Gallbladder (GB) cancer (GBC) is a malignancy with a poor prognosis. The 5-year survival rate of unresected GBC is approximately 0%, and the 3-year survival rate of advanced GBC remains at <20% even after curative resection. 1,2 To improve the prognosis of GBC, proper diagnosis with imaging study is essential. Gallbladder cancer usually presents as a protruded lesion or wall thickening. However, some GB lesions, such as in the case of cholecystitis or adenomyomatosis, also present as a protrusion or wall thickening. This morphological similarity causes difficulties in the differentiation of benign from malignant GB lesions in imaging study. 3 To facilitate differentiation, various imaging studies have been

Novel Technique of Endoscopic Ultrasonography for the Differential Diagnosis of Gallbladder Lesions and Intraductal Papillary Mucinous Neoplasms: A Single-Center Prospective Study

“…There is only one report on the utility of SMI as a microvascular imaging technique for gallbladder lesions. In this study, which Kin et al reported that a change in the caliber of vessels significantly predicted malignant gallbladder lesions [ 30 ]. This result is consistent with that of this study.…”

G1‐Neuroendocrine tumor of gallbladder with unique dendritic morphology

“…Superb microvascular imaging with US using perfluorobutane showed irregularly branched microvessels (Video S2). 2 Bile cytological examination after endoscopic transpapillary gallbladder drainage showed no atypical cells. Though the polyps were suspected to be benign, laparoscopic cholecystectomy was performed according to the patient’s preference.…”

New microvascular ultrasound techniques: abdominal applications

“…An initial study including 20 patients also evaluated the feasibility of contrast-enhanced superb microvascular imaging for the vascular evaluation of gallbladder lesions (Fig. 3 ) demonstrating a significantly higher frequency of tortuous microvessels and abrupt caliber change in malignancies comparted to benign gallbladder lesions [ 37 ].

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“…FNH: spoke-wheel pattern (41–67%). HCC: non-specific or irregular pattern (48–93%) Assessment of treatment response [ 18 ] Detection of residual intratumoral flow after transarterial chemoembolization Fibrosis staging [ 25 – 28 ] Vascular changes can predict the severity of fibrosis Diagnosis of steatosis [ 29 ] Vascular index inversely correlated with hepatic steatosis Assessment of liver transplant recipients [ 30 – 33 ] Improved visibility of the hepatic artery and diagnosis of hepatic artery thrombosis Gallbladder Diagnosis of acute cholecystitis [ 34 ] Superb microvascular imaging value predicted acute cholecystitis Diagnosis of gallbladder lesions [ 37 ] Superb microvascular imaging may help in the differential diagnosis Kidney Differential diagnosis between renal lesions [ 41 – 45 ] Improved detection of intratumoral vascularization. Malignant tumors: annular or ring-like flow pattern (65–67%) Diagnosis of acute pyelonephritis [ 46 ] Improved detection and diagnosis Evaluation of renal function [ 47 , 48 ] Cortical flow and vascular index correlated with the severity of chronic kidney disease Bladder Acute cystitis [ 50 ] Higher vascular index was associated with acute cystitis Vesicoureteral reflux [ 51 ] Demonstrated reversed ureteral jet and/or renal pelvic swirl sign Prostate Diagnosis of prostate cancer [ 52 , 53 ] Higher vascularity in malignant lesions and lesions with...…”