2018
DOI: 10.5114/pdia.2017.71257
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Efficacy of suction blister epidermal grafting with concomitant phototherapy in vitiligo treatment

Abstract: A b s t r a c tIntroduction: There are many surgical methods for vitiligo treatment that have been used for over 30 years. Suction blister epidermal grafting (SBEG) is considered one of the simplest and most effective of them. Aim: To determine how effective suction blister grafts with concomitant phototherapy are in vitiligo treatment. Material and methods: The study was conducted on 10 patients with vitiligo that was resistant to previous treatment including phototherapy in monotherapy. Involvement of affect… Show more

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Cited by 7 publications
(8 citation statements)
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“…We analyzed a total of 117 unique studies with 8776 unique patients (eTable 1 in the Supplement), including 19 studies with 1631 patients in the punch grafting group, 10 studies with 718 patients in the thin skin grafting group, 29 studies with 2652 patients in the suction blister grafting group, 45 studies with 2209 patients in the noncultured epidermal cell suspension (NCES) group, 9 studies with 185 patients in the noncultured follicular cell suspension (NCFS) group, and 17 studies with 1381 patients in the cultured epidermal cell suspension (CES) group; 11 studies included more than 1 procedure type. The median follow-up duration was 7 (range, 2-108) months.…”
Section: Resultsmentioning
confidence: 99%
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“…We analyzed a total of 117 unique studies with 8776 unique patients (eTable 1 in the Supplement), including 19 studies with 1631 patients in the punch grafting group, 10 studies with 718 patients in the thin skin grafting group, 29 studies with 2652 patients in the suction blister grafting group, 45 studies with 2209 patients in the noncultured epidermal cell suspension (NCES) group, 9 studies with 185 patients in the noncultured follicular cell suspension (NCFS) group, and 17 studies with 1381 patients in the cultured epidermal cell suspension (CES) group; 11 studies included more than 1 procedure type. The median follow-up duration was 7 (range, 2-108) months.…”
Section: Resultsmentioning
confidence: 99%
“…Overall, the rate of repigmentation achieved by patients after 1 session of any surgical intervention included greater than 90% in 52.69% (95% CI, 46.87%-58.50%) in 106 studies with 6586 patients ( I 2 = 97.2%) (eFigure 2 in the Supplement); greater than 75% in 64.72% (95% CI, 59.52%-69.92%) in 100 studies with 3400 patients ( I 2 = 95.7%); and greater than 50% in 81.01% (95% CI, 78.18%-83.84%) in 92 studies with 5462 patients ( I 2 = 90.7%). According to the surgical intervention type, greater than 90% repigmentation was achieved in 72.08% (95% CI, 54.26%-89.89%) of patients undergoing thin skin grafting (670 patients in 8 studies), 61.68% (95% CI, 47.44%-75.92%) of patients undergoing suction blister grafting (2349 patients in 21 studies), 56.82% (95% CI, 48.93%-64.71%) of patients undergoing CES (1138 patients in 14 studies), 47.51% (95% CI, 37.00%-58.03%) of patients undergoing NCES (907 patients in 29 studies), 45.76% (95% CI, 30.67%-60.85%) of patients undergoing punch grafting (1354 patients in 11 studies), and 36.24% (95% CI, 18.92%-53.57%) of patients undergoing NCFS (160 patients in 8 studies) after 1 session of each surgery (eFigure 2 in the Supplement and Table 1). In our meta-regression analysis, for greater than 90% repigmentation, the estimate of the slopes for mean age of patients was −1.1418 ( P = .02); for the proportion of segmental vitiligo, 0.3047 ( P = .01); and for the proportion of treated lesions on the acral and joint areas, −0.4050 ( P = .002) (Figure 2).…”
Section: Resultsmentioning
confidence: 99%
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“…Dostępne obecnie metody obejmują: leczenie miejscowe, ogólne, fototerapię, laseroterapię, metody chirurgiczne, kosmetyczne, leczenie wspomagające oraz psychoterapię. W wielu publikacjach opisywano terapie łączone z wykorzystaniem fototerapii oraz innych form leczenia w celu przyspieszenia procesu repigmentacji [18][19][20]. Repigmentację ognisk chorobowych można uzyskać, wywołując migrację melanocytów z mieszków włosowych (repigmentacja przymieszkowa) bądź rzadziej z obwodu odbarwienia (repigmentacja obwodowa) [3,21], Należy pamiętać, że większość leków używanych w terapii bielactwa nabytego jest stosowana poza wskazaniami rejestracyjnymi (off-label), co należy uwzględnić w dokumentacji chorych i postępować zgodnie z obowiązującymi w tym zakresie przepisami.…”
Section: Topical Treatmentunclassified
“…There are many surgical methods for vitiligo treatment that have been used for over 30 years. Suction blister epidermal grafting (SBEG) is considered one of the simplest and most effective of them [ 30 ]. There are some modifications of this method such as SBEG with CO 2 laser ablation which offers simple and safe treatment of vitiligo, especially for patients with small and stable vitiliginous lesions [ 31 ].…”
Section: Introductionmentioning
confidence: 99%