Efficacy of sclerotherapy with radio-opaque foam guided by digital subtraction angiography for the treatment of complex venous malformations of the head and neck

Chen, A.-W.; Liu, Yan‐Rui; Li, K.; Zhang, K.; Wang, T.; Liu, S.-H.

doi:10.1016/j.bjoms.2015.05.024

Cited by 15 publications

(9 citation statements)

References 16 publications

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“…The high efficiency of foam sclerotherapy was closely related to the physical obstruction of blood flow and the displacing the intravascular blood, which extended extent of contaction between the sclerosants and the vessel wall (Ikponmwosa et al 2010 ; Wolmann 2010 ; Eckmann 2009 ; Van Deurzen et al 2011 ). Therefore, the therapeutic effects related to whether the cavity of VMs could be replete by fresh sclerosing foam; In our clinical work, sometime more than 10 ml fresh sclerosing foam was needed for extensive lesion, some authors found that 10 ml or more sclerosing foam was safety and efficacy, and no serious complications were observed (Stimpson et al 2012 ; Chen et al 2015 ). In our experience, the most common complications were temporal pain with injection, swelling after injection and skin ulcer in some patients.…”

Section: Discussionmentioning

confidence: 73%

A modified Tessari method for producing more foam

Wang

et al. 2016

SpringerPlus

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This study aimed to develop a modified Tessari method for producing more sclerosing foam in treatment of extensive venous malformations. Sclerosing foam was produced by using Tessari method and the modified Tessari method. The procedure of the later was as follows: prepared foam in a sclerosant–air ratio of 1:4; connected three disposable 10 ml syringes to two medical three-way taps; drawn 4 ml of liquid sclerosant into one syringe and 16 ml averagely of air into the other two; then moved the plungers of all syringes back and forth for 20 times to produce sclerosing foam. The volume and foam half time (FHT) of foam produced by the two methods were compared. The average volume of sclerosing foam produced by Tessari method and the modified Tessari method were 9.8 and 19.7 ml, and assessed to have statistical difference. The FHT of foam produced by the two methods were 120 and 150 s, and assessed to have statistical difference. In conclusion, the modified Tessari method could produce more fresh and stable sclerosing foam.

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Section: Discussionmentioning

confidence: 73%

A modified Tessari method for producing more foam

Wang

et al. 2016

SpringerPlus

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“…After thoroughly reading and discussing the remaining 45 articles, 34 publications were excluded. Finally, 11 publications with 305 patients were selected for the meta-analysis (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). The quality of the included publications was relatively low.…”

Section: Literature Search Description and Quality Of The Included St...mentioning

confidence: 99%

Effectiveness of Polidocanol in the Treatment of Venous Malformations: A Meta-Analysis

Liu

Sun

et al. 2022

Front. Pediatr.

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ObjectiveThe aim of this study was to investigate the efficacy of polidocanol against venous malformations (VMs).MethodsStudies reporting the treatment of VMs using polidocanol (published until February 15, 2020) were reviewed in the Embase and PubMed databases. After excluding the same literature, part of the studies were excluded by reading the title, abstract, full text. Eleven studies (with 287 participants) that fulfilled the inclusion criteria were included. Systematic meta-analysis was performed using Reviews Manager 5.2, and a fixed-effects model was used to calculate the pooled effective rate of polidocanol against VMs and the 95% confidence intervals (CI).ResultsLesion reduction of more than 50% was considered effective. A total of 287 patients were treated, and treatment in 271 was considered effective. The efficacy of polidocanol was 0.89 (95% CI = 0.83–0.93). Heterogeneity among the studies was small (I2 = 0%, P = 0.47). T The funnel plot was roughly symmetric.ConclusionOur study suggested that polidocanol is effective in the treatment of VMs. VMs at different sites can be treated without serious complications. Therefore, we have reason to believe that polidocanol is a safe and an effective drug for VMs.

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“…Most of the included studies involved heterogeneous patients. First, about two thirds of studies included both children and adults [ 7 , 19 – 21 , 23 – 27 , 29 – 34 , 36 , 38 – 84 ]. Second, nearly one third were of several diseases [ 7 , 22 , 27 , 29 , 30 , 33 , 38 , 40 , 45 , 50 , 52 , 54 , 55 , 57 , 58 , 60 , 64 , 65 , 67 , 68 , 74 , 77 , 79 , 84 – 86 ].…”

Section: Resultsmentioning

confidence: 99%

Designs used in published therapeutic studies of rare superficial vascular anomalies: a systematic literature search

Allemang-Trivalle,

Leducq,

Maruani

et al. 2023

BMC Med Res Methodol

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Background Rare superficial vascular anomalies represent a wide range of diseases. Their management is difficult given the broad spectrum and the lack of clinical trials assessing treatment efficacy. A randomized clinical trial of vascular anomalies is difficult because of the rarity of the diseases and is enhanced by the population of interest often being children. Therefore, suitable designs are needed. We conducted a methodological systematic literature search to identify designs implemented for investigating the treatment of rare superficial vascular anomalies. Methods We conducted a literature search on January 25, 2021, of the PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, ClinicalTrials.gov and European Union Clinical Trials Register databases. This systematic methodological literature search was registered at the Prospective Register of Systematic Reviews (PROSPERO: CRD42021232449). Randomized and non-randomized studies were included if they met the following criteria: were prospective studies of rare superficial vascular anomaly therapies, dealt with humans (adults and children) and were published in English from 2000. We excluded case reports/case series reporting fewer than 10 patients, reviews, retrospective studies, animal studies, studies of systemic or common vascular anomalies and non-therapeutic studies. We did not assess risk of bias in the included studies because our review was a methodological one focused on the design used. The review provided a descriptive analysis of relevant features of eligible research studies. Results From 2046 articles identified, we included 97 studies (62 reports and 35 ongoing studies): 25 randomized controlled studies, 7 non-randomized comparative studies, 64 prospective cohorts and 1 case series. Among the 32 comparative studies included, 21 used a parallel-group design. The 11 other studies used different designs such as cross-over, randomized placebo phase, delayed-start, within-person, or challenge–dechallenge–rechallenge or used a historical control group or an observational run-in period. Conclusions Our systematic literature search highlights the lack of randomized control trials in superficial vascular anomalies due to the rarity of patients and their heterogeneity. New designs are emerging and can overcome the limitations of testing treatments in parallel groups.

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Efficacy of sclerotherapy with radio-opaque foam guided by digital subtraction angiography for the treatment of complex venous malformations of the head and neck

Cited by 15 publications

References 16 publications

A modified Tessari method for producing more foam

A modified Tessari method for producing more foam

Effectiveness of Polidocanol in the Treatment of Venous Malformations: A Meta-Analysis

Designs used in published therapeutic studies of rare superficial vascular anomalies: a systematic literature search

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