Efficacy of rice bran fermentation in cosmetics and skin care products

Abstract

This study aims to develop rice bran-based skin care products with moisturizing, whitening and anti-wrinkle effects similar to Pitera (a natural by-product of sake lees fermentation) but without alcohol irritation for sensitive skin. To achieve this objective, bran from organic indica rice was fermented by lactic acid bacteria in a safe and pollution-free environment. In terms of anti-oxidation, the DPPH．free radical scavenging ability of 100.0 mg/mL bran fermentation solution was 71.4% of that of vitamin C of the same concentration; and its Fe 2+ chelating ability was 79.0% of that of EDTA of the same concentration. Moreover, the superoxide anion scavenging ability of 10.0 mg/mL bran fermentation solution was equivalent to 42.9% of that of BHT of similar concentration. With respect to inhibition of melanin synthesis, the bran fermentation solution's ability to inhibit the synthesis of dopachrome, the intermediate of melanin, was positively correlated to its concentration, i.e., the higher the concentration of the bran fermentation solution was, the better the inhibition ability was. The IC 50 of bran fermentation solution was 9.23 mg/mL while, for comparison, that of arbutin was 0.52 mg/mL. Furthermore, according to the cell survival assay, no obvious cytotoxic effect was found with the increase of the concentration of the bran fermentation solution. As for whitening evaluation, the whitening improvement rate was 9.29% in 20% dilution, 5.36% in 15% dilution, 3.69% in 10% dilution, 2.43% in 5% dilution, 0.35% in 1% dilution in a 30-day test. In the moisturizing evaluation, the moisturizing improvement rate was 44.31% in 20% dilution, 20.48% in 15% dilution, 7.68% in 10% dilution, 6.02% in 5% dilution and 2.02% in 1% dilution. Based on the experimental results, the alcohol-free rice bran fermentation solution not only did not cause irritation but also had antiaging, melanin synthesis inhibition, whitening and moisturizing effects. Therefore, it is advisable to add rice bran fermentation solution to cleaning mousse, shower gel, serum and essence to turn bran from compost of agricultural waste (cradle to grave) into a natural raw material (cradle to cradle) of the cosmetic industry, creating new value of rice bran.

Functional Properties of an Oat-Based Postbiotic Aimed at a Potential Cosmetic Formulation

“…Juan and Chou [52] carried out a solid-state fermentation of black soybeans with Bacillus subtilis BCRC 14715 to evaluate the effect of fermentation on antioxidant activity: a final EC 50 value of 30.7 mg sample /mg DPPH was found. Moreover, Chen et al [53] developed a rice-bran-based skin care product through the fermentation of rice bran using lactic acid bacteria; the EC 50 value determined for the fermented rice bran was 811.5 mg sample /mg DPPH , higher than that obtained in this study, suggesting a higher antioxidant power of the fermented oatmeal produced.…”

“…Tyrosine conversion (tyrosine peak detected at a retention time of 3.7 min) in presence of postbiotic was lower than that observed after 60 min of reaction in control solution, indicating an inhibitory effect of the functional ingredient developed in this study. The ability of a fermented rice bran solution to inhibit melanin synthesis was investigated by Chen et al [53]. A lower IC50 value of 9.23 mg/mL than that obtained in this work was reported.…”

“…Fermentation process appeared to be responsible for increasing the anti-tyrosinase activity, probably due to both the highest lactic acid content reached in the fermented matrix after 24 h of process and its increased phenolic amount, as confirmed by several literature works [53,57,58], where lactic acid and phenolic compounds were identified as the main substances responsible for the melanin inhibition process.…”

“…literature works [53,57,58], where lactic acid and phenolic compounds were identified as the main substances responsible for the melanin inhibition process.…”

Dermatological uses of rice products: Trend or true?

“…Skin care products made from fermented rice bran (FRB) have also been developed and were non‐irritating, moisturizing, antiaging, and whitening 33 . In human fibroblasts irradiated with UVB radiation, FRB extract increased type I collagen production, reduced expression of collagen degrading matrix metalloprotease 1, and decreased levels of IL‐1α.…”