Efficacy of <i>Insulclock</i> in Patients with Poorly Controlled Type 1 Diabetes Mellitus: A Pilot, Randomized Clinical Trial

Gómez-Peralta, Fernando; Abreu, Cristina; Gomez-Rodriguez, Sara; Cruz-Bravo, Margarita; María-Sanchez, Cristina; Poza, Gema de la; Ruiz-Valdepeñas, Luis

doi:10.1089/dia.2019.0427

Cited by 21 publications

(25 citation statements)

References 23 publications

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“…Patients on intensive insulin regimens should assess glucose levels regularly by either self-monitoring of blood glucose or CGM (36). The fact that 73% of adults and 91% of parents of children with type 1 diabetes in our survey were using CGM is reassuring, as close glucose monitoring is needed to monitor and optimize the use of ultra-fast-acting insulin.…”

Section: Discussionmentioning

confidence: 88%

“…Such tools will inevitably reduce the number of missed bolus doses in people with diabetes. “Smart” insulin pens can be programmed to calculate insulin doses to assist patients in real time and provide downloadable data reports allowing treating physicians to retrospectively review doses and make adjustments as needed ( 37 ). Sensor-augmented pumps, now approved by the U.S. Food and Drug Administration, are designed to suspend insulin dosing when they either detect low glucose or predict a fall in glucose within the next 30 minutes ( 3 ).…”

Section: Discussionmentioning

confidence: 99%

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Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

et al. 2021

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Timely and accurate mealtime insulin dosing can be an ongoing challenge for people with type 1 diabetes. This multinational, online study aimed to explore attitudes and behaviors around mealtime insulin dosing and the impact of mealtime dose timing, particularly with regard to premeal dosing (15–20 minutes before a meal). Although the majority of surveyed participants (96%) recognized the importance of accurate mealtime bolus insulin dosing, only a small proportion (35%) reported being “very confident” in accurate bolus insulin estimation. Given the choice, the majority of participants would prefer to administer insulin immediately before or after a meal, as this timing would improve their quality of life.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

et al. 2021

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“…Moreover, individual reminders allow to keep the schedule of basal insulin ( 136 ). Similarly, Insulclock ® is an electronic device attached into the insulin pen and connected with a smartphone app and has an insulin reminder system to reduce insulin omissions ( 137 ); this device helps to improve glycemic control and reduce glycemic variability with improved adherence in a recent pilot, randomized study among T1DM ( 138 ) and among T2DM patients ( 139 ). Another two devices do not connect with any mobile app but present an interactive display (Timesulin ® ) or flash diode (Dukada ® Trio), which define the time of last insulin injection ( 140 , 141 ).…”

Section: Insulin Pen Capsmentioning

confidence: 99%

The Review of Insulin Pens—Past, Present, and Look to the Future

et al. 2022

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Currently, there are about 150–200 million diabetic patients treated with insulin globally. The year 2021 is special because the 100th anniversary of the insulin discovery is being celebrated. It is a good occasion to sum up the insulin pen technology invention and improvement which are nowadays the leading mode of an insulin delivery. Even though so many years have passed, insulin is still administered subcutaneously, that is why devices to deliver it are of great importance. Insulin pens have evolved only through the last decades (the reusable, durable pens, and the disposable, prefilled pens) and modern smart insulin pens have been developed in the last few years, and both types of the devices compared to traditional syringes and vials are more convenient, discrete in use, have better dosing accuracy, and improve adherence. In this review, we will focus on the history of insulin pens and their improvement over the previous decades.

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“…"Smart" pens that can be programmed to calculate insulin doses and provide downloadable data reports are also available. These pens are useful to assist patient insulin dosing in real time as well as for allowing clinicians to retrospectively review the insulin doses that were given and make insulin dose adjustments (114).…”

Section: Side Effects Of Cgm Devicesmentioning

confidence: 99%

7. Diabetes Technology: Standards of Medical Care in Diabetes—2021

2020

Diabetes Care

176

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The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc21-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc21-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.

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Efficacy of Insulclock in Patients with Poorly Controlled Type 1 Diabetes Mellitus: A Pilot, Randomized Clinical Trial

Cited by 21 publications

References 23 publications

Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

Exploring the Burden of Mealtime Insulin Dosing in Adults and Children With Type 1 Diabetes

The Review of Insulin Pens—Past, Present, and Look to the Future

7. Diabetes Technology: Standards of Medical Care in Diabetes—2021

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