Efficacy of flax oil in preventing postoperative peritoneal adhesions

Ayşan, Erhan; Bektaş, Hasan; Kaygusuz, Arslan; Huq, Gülben Erdem

doi:10.1007/s10353-009-0453-1

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…In this study, we investigated the effectiveness of glycerol and flax seed oil in preventing post-thyroidectomy adhesions, neither of which had been used for this purpose before. Aysan et al evaluated flax seed oil and glycerol for effectiveness in preventing postoperative peritoneal adhesions in 2 separate studies, both of which found that flax seed oil and glycerol significantly decreased peritoneal adhesion formation [ 37 , 38 ]. Building on these studies, we evaluated the effectiveness of flax seed oil and glycerol in preventing post-thyroidectomy adhesions.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy

et al. 2014

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BackgroundWe evaluated the effects of local flax seed oil and glycerol application for reducing adhesion formation after thyroidectomy.Material/MethodWe randomly assigned 18 female Wistar albino rats (median weight: 275 g, median age: 4.5 mth) to 3 groups: 0.1 ml 0.9% NaCl, glycerol, and flax seed oil were sprayed in a perithyroidal area after thyroidectomy operation on all animals as anti-adhesive barriers. Rats were sacrificed on the postoperative 14th day and adhesions were evaluated macroscopically and microscopically.ResultsThe median macroscopic adhesion score was 3.0±0.0 in the 0.9% NaCl group, 1.33±0.52 in the glycerol group, and 1.67±0.53 in the flax seed oil group. The median histopathological fibrosis scores were 2.33±0.82, 0.67±0.52, and 0.83±0.75, respectively. Both glycerol and flaxseed oil group macroscopic and microscopic scores were significantly lower than the 0.9% NaCl group (p<0.05). There was no significant difference among the groups (p>0.05).ConclusionsGlycerol and flax seed oil both decrease the incidence of post-thyroidectomy adhesion in rats, but glycerol is more effective.

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Section: Discussionmentioning

confidence: 99%

Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy

et al. 2014

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“…In the absence of adhesions, intraperitoneal 0.1 mL of the following sterile viscous liquids was injected interperitoneally in five subgroups: Group 2.1 ( n = 10): soybean oil [ 6 ], Group 2.2 ( n = 10): octyl methoxycinnamate [ 7 ], Group 2.3 ( n = 10): flax seed oil [ 8 ], Group 2.4 ( n = 10): aloe vera gel [ 9 ], Group 2.5 ( n = 10): glycerol [ 10 ]. …”

Section: Methodsmentioning

confidence: 99%

New and Simple Approach for Preventing Postoperative Peritoneal Adhesions: Do not Touch the Peritoneum without Viscous Liquid—A Multivariate Analysis

Ayşan

Bektaş

Ersöz

et al. 2012

Obstetrics and Gynecology International

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Background. Postoperative peritoneal adhesions (PPAs) are an unsolved and serious problem in abdominal surgery. Method. Viscous liquids of soybean oil, octyl methoxycinnamate, flax oil, aloe vera gel, and glycerol were used in five experiments, using the same methodology for each. Liquids were applied in the peritoneal cavity before and after mechanical peritoneal trauma. Results were evaluated by multivariate analysis. Results. Compared with the control group, macroscopic and microscopic adhesion values before (P < .001) and after (P < .05) application of viscous liquids significantly reduced PPAs. Values were significantly lower when liquids were applied before rather than after peritoneal trauma (P < .0001). Discussion. Viscous liquids injected into the peritoneal cavity before or after mechanical peritoneal trauma decrease PPA. Injection before trauma was more effective than after trauma. In surgical practice, PPA formation may be prevented or decreased by covering the peritoneal cavity with an appropriate viscous liquid before abdominal surgery.

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The fascinating spectrum of surgery

Riegler

2009

Eur Surg

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Efficacy of flax oil in preventing postoperative peritoneal adhesions

Cited by 3 publications

References 22 publications

Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy

Efficacy of glycerol and flax seed oil as anti-adhesive barriers after thyroidectomy

New and Simple Approach for Preventing Postoperative Peritoneal Adhesions: Do not Touch the Peritoneum without Viscous Liquid—A Multivariate Analysis

The fascinating spectrum of surgery

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