Efficacy of enhanced <i>Escherichia coli</i> phytase on growth performance, bone quality, nutrient digestibility, and metabolism in nursery pigs fed corn-soybean meal diet low in calcium and digestible phosphorous

Kiarie, E.; Song, Xuerong; Lee, Junhyung; Zhu, Cuilan

doi:10.1093/tas/txac020

Cited by 3 publications

(3 citation statements)

References 31 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Differences in serum Ca concentrations coincided with differences in urinary Ca excretion, which is consistent with the results of Schlegel and Gutzwiller (2017) . The serum ALP activity was decreased with the addition of phytase, which is consistent with the study of Kiarie et al (2022) , who observed a decrease in plasma ALP activity in nursery pigs with the addition of exogenous phytase to a low-P corn-based diet. The calculated hindgut disappearance of P and Ca did not differ, and the values were close to zero, indicating no net absorption of these minerals in the hindgut.…”

Section: Discussionsupporting

confidence: 90%

Effect of dietary calcium concentration and exogenous phytase on inositol phosphate degradation, mineral digestibility, and gut microbiota in growing pigs

Klein

Sarpong

Melzer

et al. 2023

Journal of Animal Science

View full text Add to dashboard Cite

Variations in the dietary Ca concentration may affect inositol phosphate (InsP) degradation, and thereby, P digestibility in pigs. This study assessed the effects of dietary Ca concentration and exogenous phytase on InsP degradation, nutrient digestion and retention, blood metabolites, and microbiota composition in growing pigs with ileal cannulation. In a completely randomized row-column design with four periods, eight ileal-cannulated barrows (initial BW 27 kg) were fed four corn-soybean-and rapeseed meal-based diets containing 5.5 or 8.5 g Ca/kg DM, with or without 1,500 FTU of an exogenous hybrid-6-phytase/kg diet. No mineral P was added and the P concentration in the feed was 4.8 g P/kg DM. Prececal InsP6 disappearance in pigs fed diets containing exogenous phytase was lower (P = 0.022) with additional Ca than without. Concentrations of InsP2-4 isomers and myo-inositol in the distal ileal digesta and prececal P digestibility were greater (P < 0.001) with exogenous phytase than without exogenous phytase. In feces, InsP6 disappearance was lower (P < 0.002) and concentration of InsP5 and InsP4 isomers was higher (P ≤ 0.031) with additional Ca compared to without additional Ca. The prececal amino acid digestibility, energy digestibility, and hindgut disappearance of energy did not differ. The Shannon diversity index of the microbiota in the distal ileal digesta and feces was similar among the diets but was lower in the distal ileal digesta than in the feces (P < 0.001). Permutation analysis of variance revealed no dietary differences between the bacterial groups within the ileal digesta and fecal samples (P > 0.05). In conclusion, additional Ca reduced the effect of exogenous phytase on prececal InsP6 degradation. Endogenous InsP degradation was impaired by additional Ca only in the hindgut but the abundance of bacterial genera in feces was not affected.

show abstract

Section: Discussionsupporting

confidence: 90%

Effect of dietary calcium concentration and exogenous phytase on inositol phosphate degradation, mineral digestibility, and gut microbiota in growing pigs

Klein

Sarpong

Melzer

et al. 2023

Journal of Animal Science

View full text Add to dashboard Cite

show abstract

“…Enzyme-treated GRP pomace had a significantly higher plasma ALP compared to the rest of the enzyme-treated and non-enzyme-treated pomaces. Increase in plasma ALP has also been noted in pigs fed diets supplemented with phytase enzyme linked with increased bone mineralization (Kiarie et al 2022). Additionally, there were non-significant differences in ALP levels between the enzymetreated and non-enzyme-treated pomaces.…”

Section: Discussionmentioning

confidence: 92%

Utilization of grape (Vitis vinifera), cranberry (Vaccinium macrocarpon), wild blueberry (Vaccinium angustifolium), and apple (Malus pumila/domestica) pomaces in broiler chickens when fed without or with multi-enzyme supplement

et al. 2023

Self Cite

View full text Add to dashboard Cite

Nutritive and functional value of fruit pomaces in poultry is unexplored. We determined apparent metabolizable energy (AME) and plasma metabolites in broiler chickens fed diets containing apple (APL), low bush wild blueberry (LBP), cranberry (CRP) and grape (GRP) pomaces without or with multi-enzyme supplement (ENZ). A total of 360 one-d old Ross 708 male chicks were placed in 72 cages; 5 birds/cage, were reared to d 13 and transitioned to either cornstarch-soy protein isolate basal diet or basal with 30% of either pomace without or with ENZ. Excreta samples were collected from d 17 to 20 and one bird/cage bled for plasma metabolites on d 21. Apple pomace showed a higher AME (P=0.008) than other pomaces, however, ENZ had no effect on AME. The AME was 3,250, 2,613, 2,394 and 3,008 kcal/kg DM for APL, LBP, CRP, and GRP, respectively. There was pomace and ENZ interaction on plasma alkaline phosphatase (P = 0.04) and APL increased cholesterol levels (P < 0.01). In conclusion, ENZ had no impact on energy increment in pomaces, but the AME values this study has established are nonetheless valuable for accurate poultry feed formulation. Plasma metabolites suggested pomace components are amenable to supplemental ENZ.

show abstract

“…In fact, P is an indispensable nutrient needed for normal growth, and it plays important roles in vital functions, such as energy and amino acid metabolism, protein synthesis, and maintaining acid–base balance [ 27 , 28 , 29 , 30 ]. Several studies have reported improvements in performance when phytase was used in piglets and growing pigs [ 21 , 31 , 32 , 33 , 34 , 35 ]. In the current study, the addition of phytase at 500 FTU/kg diet improved the growth performance and feed efficiency of nursery and growing–finishing pigs fed diets reduced in digestible P and Ca.…”

Section: Discussionmentioning

confidence: 99%

A New Biosynthetic 6-Phytase Added at 500 Phytase Unit/kg Diet Improves Growth Performance, Bone Mineralization, and Nutrient Digestibility and Retention in Weaned Piglets and Growing–Finishing Pigs

Jlali,

Hincelin,

Torrallardona

et al. 2024

Veterinary Sciences

View full text Add to dashboard Cite

Two experiments were performed to evaluate the effect of a biosynthetic 6-phytase added at 500 phytase unit (FTU)/kg diet on growth performance, bone mineralization, and nutrient digestibility and retention in weaned piglets and growing–finishing pigs. Experiments were performed on 90 weaned male and female piglets with an average initial body weight (BW) at 7.7 ± 0.73 kg, 26 days of age) and 300 male and female growing pigs (initial BW: 21.0 ± 3.44 kg) for 43 and 98 days in experiments 1 and 2, respectively. In each experiment, the animals were assigned to one of three treatments according to a randomized complete block design. The treatments consisted of a positive-control (PC) diet formulated to meet nutrient requirements; a negative-control (NC) diet reduced similarly in calcium (Ca) and digestible P by 0.15 and 0.12% points in phases 1 and 2, respectively, in piglets and by 0.14, 0.11, and 0.10% points, respectively, in phases 1, 2, and 3 in growing–finishing pigs, compared with PC diet; and a NC diet supplemented with the new 6-phytase at 500 FTU/kg diet (PHY). The dietary P and Ca depletion reduced (p < 0.05) the final BW (−11.9%; −7.8%,), average daily gain (ADG, −17.8%; −10.1%), average daily feed intake (ADFI, −9.9%; −6.0%), gain-to-feed (G:F) ratio (−8.9%; −4.6%), and apparent total tract digestibility (ATTD) of P (−7.7% points; −6.7% points) in nursery piglets and growing pigs, respectively. It also decreased (p < 0.001) P and Ca retention by 6.1 and 9.4% points, respectively, in nursery pigs and ash, P, and Ca contents in metacarpal bones by 18.4, 18.4, and 16.8%, respectively, in growing pigs. Compared to animals fed the NC diet, phytase supplementation improved (p < 0.001) the final BW (+7.7%; +11.3%), ADG (+12.5%; +15.0%), G:F ratio (+8.4%; +5.8%), ATTD of Ca (+10.8% points; +7.2% points), and ATTD of P (+18.7% points; +16.6% points) in weaned piglets and growing pigs, respectively. In addition, phytase also increased (p < 0.001) P and Ca retention by 6.1 and 9.4% points, respectively, in nursery pigs and ash, P, and Ca contents in metacarpal bones by 17.7, 15.0, and 15.2%, respectively, in growing pigs. The final BW, ADG, G:F ratio, and bone traits in animals fed the NC diet supplemented with phytase were comparable to animals fed the PC diet. This finding indicates the ability of this novel biosynthetic phytase to restore performance and bone mineralization by improving the availability of P and Ca in piglets and growing pigs fed P- and Ca-deficient diets.

show abstract

Efficacy of enhanced Escherichia coli phytase on growth performance, bone quality, nutrient digestibility, and metabolism in nursery pigs fed corn-soybean meal diet low in calcium and digestible phosphorous

Cited by 3 publications

References 31 publications

Effect of dietary calcium concentration and exogenous phytase on inositol phosphate degradation, mineral digestibility, and gut microbiota in growing pigs

Effect of dietary calcium concentration and exogenous phytase on inositol phosphate degradation, mineral digestibility, and gut microbiota in growing pigs

Utilization of grape (Vitis vinifera), cranberry (Vaccinium macrocarpon), wild blueberry (Vaccinium angustifolium), and apple (Malus pumila/domestica) pomaces in broiler chickens when fed without or with multi-enzyme supplement

A New Biosynthetic 6-Phytase Added at 500 Phytase Unit/kg Diet Improves Growth Performance, Bone Mineralization, and Nutrient Digestibility and Retention in Weaned Piglets and Growing–Finishing Pigs

Contact Info

Product

Resources

About