Efficacy of Deep Venous Thrombosis Prophylaxis in Trauma Patients and Identification of High-Risk Groups

Dennis, James W.; Menawat, Sunil S.; Thron, John Von; Fallon, William F.; Vinsant, G OʼNeal; Laneve, Lillian M.; Jagger, Claire; Frykberg, Eric R.

doi:10.1097/00005373-199307000-00021

Cited by 130 publications

(60 citation statements)

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“…There was no significant difference in VTE events with the use of electrostimulation [30] or ambulatory compared to bed-based calf compression devices [29]. There was no significant difference in DVT or PE events between the use of IPC and LMWH [25] or LDH when compared to using calf compression devices [5,7]. However the evidence-base was small in size and presented a number of major methodological limitations.…”

Section: Discussionmentioning

confidence: 99%

“…To assess the incidence of VTE, the studies all used ultrasonography, which has been shown to be a valid and reliable assessment method [21,22]. In all but two studies, the intervention groups were controlled so that all patients received the same treatment except the treatment under investigation [5,7]. No studies blinded their patients to the form of thromboprophylaxis provided.…”

Section: Critical Appraisalmentioning

confidence: 99%

“…Two papers were identified which compared the incidence of VTE when using LDH to calf compression as forms of thromboprophylaxis [5,7]. On meta-analysis, there was no statistically significant difference in relative risk in the incidence of VTE between those patients who received LDH compared to calf compression in these studies (RR = 1.66; 95% CI: 0.22-12.70; p = 0.63; I 2 = 63%; Fig.…”

Section: Low Dose Heparin Versus Calf Compressionmentioning

confidence: 99%

“…Dennis et al [5] Elliott et al [28] Fuchs et al [27] Geerts et al [23] Ginzburg et al [25] Knudson et al [7] Knudson et al [24] Murakami et al [29] Stannard et al [26] Velmahos et al [3] Clearly focused question…”

Section: Low Molecular Weight Heparin Versus Low Molecular Weight Hepmentioning

confidence: 99%

“…Whilst advances have been made in traumatology and thromboprophylaxis over the past 50 years, VTE remains a source of morbidity and mortality in trauma patients [2,3]. Venous thromboemobolism is also a life-threatening complication following major trauma [4][5][6][7]. The incidence of pulmonary embolism (PE) is estimated to be between 2 and 22% of all trauma patients, whilst deep venous thrombosis (DVT) is seen in up to 60% of this population [8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

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