Efficacy of Ashwagandha (Withania somnifera Dunal. Linn.) in the management of psychogenic erectile dysfunction

Abstract

Erectile dysfunction (ED) has been defined as the persistent inability to attain and maintain an erection sufficient to permit satisfactory sexual performance. By 2025, men with ED will be approximately 322 million, an increase of nearly 170 million men from 1995. The present study was aimed to evaluate the efficacy of Ashwagandha (Withania somnifera) in the management of psychogenic erectile dysfunction. In this study, a total of 95 patients with psychogenic erectile dysfunction satisfying the DSM IV TR diagnostic criteria were selected, out of them 86 patients completed the course of treatment. In Trial Group, Ashwagandha root powder and in Control group, Placebo (Wheat powder) were given for 60 days. Treatment selection and its allocation were done by following computerized randomization plan. Criterion of assessment was based on the scoring of International Index of Erectile Function (IIEF) Scale. Paired and Unpaired t test were used for statistical analysis. In Trial group (n=41), 12.6% and in Control group (n=45), 19.11% of improvement was observed with the significance of (P<0.001). There was no significant difference (P>0.05) found in between the two groups. Both Ashwagandha and Placebo provided no relief (<25% improvement on IIEF) in psychogenic erectile dysfunction.

Kadın cinsel fonksiyon bozukluklarında fitoterapi

“…[33] Ashwagandha (Withania Somnifera) Ashwagandha veya "Hint ginsengi" olarak da bilinen Withania somnifera geleneksel Hint tıbbında 3000 yılı aşkın bir süredir kullanılan önemli bir bitkidir. [53][54] Gençleştirici etkisi olduğundan dolayı Hint ginsengi olarak adlandırılsa da etkileri ginsengle tamamen aynı olmayıp vücutta farklı spesifik etkiler meydana getirmektedir. [54] Vücudun fiziksel ve psikolojik durumunu iyileştirmenin yanı sıra afrodizyak, sakinleştirme, gençleştirme, yaşam uzatma, enerji verme, stresle baş etmeyi kolaylaştırma gibi etkilerinin olduğu belirtilmektedir.…”

“…[54] Vücudun fiziksel ve psikolojik durumunu iyileştirmenin yanı sıra afrodizyak, sakinleştirme, gençleştirme, yaşam uzatma, enerji verme, stresle baş etmeyi kolaylaştırma gibi etkilerinin olduğu belirtilmektedir. [53,55] Günümüze kadar, Ashwagandha afrodizyak olarak çoğunlukla erkek cinsel fonksiyon bozukluğunu ve üreme yeteneğini geliştirmek için kullanılmış ve klinik çalışmalarda erkekler üzerinde yapılmıştır. [54] Kadınlar üzerinde yapılan randomize, plasebo kontrollü sadece bir pilot çalışmaya rastlanmıştır.…”

Role of Ashwagandha on Hematological, Biochemical, Seminal Parameters and on Serum Dheas in Psychogenic Erectile Dysfunction Patients

“…Study design, subjects of the study, inclusion and exclusion criteria, randomization and intervention were same as that of the clinical study 6 . The study was cleared by the ethical committee of the institute.…”

“…The present laboratory findings are consistent with the clinical study which was also reported negative results. The factors like demanding and uncooperative partner, interpersonal problems or conflicts between the partners, negative personality traits, significant psychopathology and high severity of the disease etc; factors produced negative result in the clinical study 20,21 . The same factors can be attributed for negative results in the laboratory findings of the present study also.…”

Premature Ejaculation – What Ayurveda & Yoga can Offer?

“…Kapikacchu (Mucuna prurience) is an aphrodisiac and also effective in improving the performance in men [16]. Ashwagandha is a vajikarana drug and also it is having properties like, anxiolytic, anti-depressant, anti-stress adaptogen and uplifts mood [17]. Shukra stambhana yapana vasti (medicated enema) is also found beneficial in PE [18].…”