Efficacy of antibiotic-impregnated external ventricular drain catheters

Muttaiyah, Sharmini; Ritchie, Stephen; John, Sayona; Mee, Edward; Roberts, Sally

doi:10.1016/j.jocn.2009.06.016

Cited by 45 publications

(31 citation statements)

References 11 publications

(11 reference statements)

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“…The first study done at Auckland City Hospital in New Zealand [19], showed a significant decrease in positive cerebrospinal fluid cultures using antibiotic impregnated EVDs in 46 CSF samples infected in the control group compared to 14 CSF samples infected in the antibiotic impregnated group (P < 0.0001). There were 6 (5%) episodes of clinical infection in the antibioticcoated group and 12 (15%) episodes of ventriculitis in the control group (P = 0.0627); however, according to the authors, due to the small sample size there was no significant effect found.…”

Section: Risk Factors For Evd Infectionsmentioning

confidence: 98%

Strategies to Decrease the Risk of Ventricular Catheter Infections: A Review of the Evidence

et al. 2011

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The use of antibiotic-coated external ventricular catheters has been controversial among practitioners; although several papers have documented decreased adherence of microbes to catheters treated with antibiotics, there is no universally accepted practice standard for the use of coated catheters for the prevention of clinical infection. In this paper, we review the in vivo and in vitro evidence for antibiotic-coated catheters.

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Section: Risk Factors For Evd Infectionsmentioning

confidence: 98%

Strategies to Decrease the Risk of Ventricular Catheter Infections: A Review of the Evidence

et al. 2011

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“…In the same study, long-term systemic use of rifamycin was reported to be toxic to the liver. Muttaiyah et al [15] reported that using clindamycin and rifamycin-soaked external ventricular drainage catheters decreased catheter-dependent ventriculitis. In the present study, a similarity was observed between the local rifamycin use and control groups.…”

Section: Discussionmentioning

confidence: 99%

Which method is the most effective for preventing postoperative infection in spinal surgery?

et al. 2015

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“…They concluded that AI-EVDs appeared safe and effective at reducing the risk of infection. Muttaiyah et al (25) also evaluated clindamycin + rifampin catheters. They considered VAI as a positive CSF culture with CSF leukocytosis > 5x10 6 /L.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%