Efficacy of an injectable formulation of eprinomectin against Psoroptes cuniculi, the ear mange mite in rabbits

Pan, Baoliang; Wang, Ming; Xu, Farong; Yuwan, Wang; Dong, Yuntang; Zhende, Pan

doi:10.1016/j.vetpar.2006.01.013

Cited by 27 publications

(19 citation statements)

References 14 publications

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“…As observed by Pan et al (2006), there have been few studies involving the development of Psoroptes ovis in rabbits. In the same study that tested eprinomectin in rabbits, the authors observed that the mite population in the control group tripled during the experimental period (day +35).…”

Section: Discussionmentioning

confidence: 99%

“…The lesion score and criteria utilized during the evaluation was as follows: 0 for apparently normal ears; 1 for lesions inside the ear; 2 for lesion on the bottom third (1/3) of the ear; 3 for lesions that extended two thirds (2/3) of the ear and 4 for lesions with a greater extension than two thirds of the ear (Pan et al 2006).…”

Section: Ethicsmentioning

confidence: 99%

“…Different drugs have been used for the treatment of these ectoparasites with good results, such as ivermectin (Pandey 1989, Stephen et al 1990, Coelho et al 2014, moxidectin (Wagner &Wendlberger 2000), eprinomectin (Pan et al 2006), selamectin (McTier et al 2003, Fisher et al 2007), permethrins (Melo et al 2008), d-phenothrin/pyriproxyfen associations , pyriprole (Batista et al 2013), and phytotherapeutic products (Maske & Kolte 1999, Joshi et al 2000, Fernandes et al 2012, Nong et al 2012, administered topically or systemically.…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of oral doramectin as treatment for Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits

et al. 2017

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The present study evaluated the efficacy of a single oral dose of doramectin in the control of Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits. Sixteen adult rabbits were selected and distributed in two experimental groups. The treated group received 200 µg/Kg of oral doramectin and the control group received the same volume of saline solution. The diagnosis of the mites was made with a stereoscopic microscope. Hairs from the dorsal part of the neck, lumbar right, lumbar left, ventral side of the tail and ventral abdomen were evaluated for L. gibbus, and ear wax evaluated for P. ovis. The evaluation of the efficiency and the clinical assessment of the lesions was made in days 0, +3, +7, +14, +21, +28, and +35 after treatment. An efficacy of 75% and 87,5% was observed for L. gibbus in days +3 and +7 after treatment, an efficacy of 100% was observed in days +14, + 21, +28 e +35. An efficacy of 100% for the control of P. ovis was observed following day +7. The clinical lesion score of the control group remained unaltered, except for one animal which conditions worsened during experimentation. In the treated group animals, regression of the lesions was observed following day +3, and on day +21 no signal of infestation by P. ovis was present. None of the animals from the treated group presented secondary collateral effects caused by the doramectin, which proved itself as an optimal alternative for mite control in naturally infested rabbits.

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Section: Discussionmentioning

confidence: 99%

Section: Ethicsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Efficacy of oral doramectin as treatment for Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits

et al. 2017

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“…O escore da lesão e o critério utilizado na avaliação das orelhas dos coelhos foram os seguintes: 0 para orelhas aparentemente normais; 1 para lesão dentro da orelha; 2 para lesão no terço inferior da orelha; 3 para lesão com extensão de dois terços inferiores da orelha e 4 para lesão com extensão maior que dois terços inferiores da orelha (Pan et al 2006).…”

Section: Methodsunclassified

Eficácia da ivermectina oral no controle de Psoroptes ovis e Leporacarus gibbus em coelhos naturalmente infestados

et al. 2014

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Pesq. Vet. Bras. 34(9):832-836, setembro 2014 832 RESUMO.-O objetivo do trabalho foi avaliar a eficácia da ivermectina administrada por via oral no controle de Psoroptes ovis e Leporacarus gibbus em coelhos naturalmente infestados. Foram selecionados 20 coelhos adultos, distribuídos na mesma proporção de ambos os sexos, em dois grupos experimentais, compondo dez animais por grupo. No grupo controle foi administrado o mesmo volume do tratamento de solução salina, enquanto o grupo tratado recebeu dose única de ivermectina oral (400 µg/Kg). O diagnóstico dos ácaros foi realizado com auxílio de microscópio estereoscópico após a devida coleta de material. Para P. ovis foi realizada através de coleta do cerúmen com auxílio de zaragatoas efetuadas nas orelhas e para por L. gibbus foi realizada coleta de pelos nas regiões do pescoço dorsal, The aim of the study was to evaluate the efficacy of oral ivermectin in the control of Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits. Twenty adult rabbits were selected; they were distributed in two groups with equal proportions of both sexes, containing ten animals per group. In the control group the same volume of the treatment was administered of saline solution, meanwhile the treated group received a single dose of oral ivermectin (400µg/kg). The diagnosis of the mites was made with a stereoscopic microscope, after the proper collection of material. For P. ovis it was performed by collecting of ear wax with swabs and for L. gibbus it was performed by collecting hairs in the dorsal part of the neck, lumbar right, lumbar left, ventral side of the tail and ventral abdomen. The evaluation of the efficiency and the clinical evaluation of the lesions, measured in scores (grade 0 to 4) was made in days 0, +3, +7, +4, +21, +28, and +35, after treatment. An efficiency of 100% was observed for P. ovis following day +7, and for L. gibbus following day +14, remaining negative until the final day of the study. The score of lesions in the ears of the treated group regressed following day +14 and on day +21 all animals reached a score of 0. In the control group, two animals presented an increase in ear lesion score, one rabbit presented an increase from score 1 to 2, and the other rabbit, from score 3 to 4. No adverse reactions were observed in the treated animals. The single dose administration of oral ivermectin was successful in the control of P. ovis and L. gibbus in naturally infested rabbits. Eficácia da ivermectina oral no controle de

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“…Dentre as principais drogas utilizadas no controle do ácaro em coelhos, destacam-se a ivermectina, moxidectina (Morrisey 1996, White et al 2002, eprinomectina (Pan et al 2006) epermetrina (Melo et al 2008). Tais drogas são muitas vezes empregadas em coelhos, mesmo não contendo indicação na bula, o que acarreta riscos no que se refere à ausência de informações sobre o período residual na carne, não informando sobre o período de carência a ser observado.…”

Section: Introductionunclassified

Eficácia acaricida de uma emulsão contendo 10% de óleo de nim (Azadirachta indica) no controle de Psoroptes ovis em coelhos naturalmente infestados

Fernandes

Verocai

Ribeiro³

et al. 2012

Pesq. Vet. Bras.

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Pesq. Vet. Bras. 32(12):1253-1256 The objective of the present study was to evaluate the efϐicacy of an emulsion containing 10% of neem (Azadirachta indica) oil on the control of Psoroptes ovis in naturally infested rabbits. Twelve rabbits were randomly divided in two groups of six animals. The control group remained without treatment; while animals in the other group were treated with the 10% neem extract formulation by spraying both ears daily for seven consecutive days. The animals were evaluated daily for the presence of adverse effects. Material from ears all animals was collected on days +3, +7, +14, +21, +28 and +35, and evaluated for the presence of living mites. Animals from control group presented mites in both ears along all days of observation. The treated group presented an efϐicacy of 41.7% on day +3 and 100% from day +7 to +35. The product containing 10% neem oil has demonstrated to be effective for the treatment of psoroptic mange on rabbits. However, treated animals presented dermatological reaction such as alopecia and hyperemia at the site of application, varying from low to medium severity.

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Efficacy of an injectable formulation of eprinomectin against Psoroptes cuniculi, the ear mange mite in rabbits

Cited by 27 publications

References 14 publications

Efficacy of oral doramectin as treatment for Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits

Efficacy of oral doramectin as treatment for Psoroptes ovis and Leporacarus gibbus in naturally infested rabbits

Eficácia da ivermectina oral no controle de Psoroptes ovis e Leporacarus gibbus em coelhos naturalmente infestados

Eficácia acaricida de uma emulsão contendo 10% de óleo de nim (Azadirachta indica) no controle de Psoroptes ovis em coelhos naturalmente infestados

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