Efficacy of a mouthwash containing 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride compared to a negative control mouthwash on dentin hypersensitivity reduction. A randomized clinical trial

Hu, Deyu; Stewart, Bernal; Mello, Sarita V.; Arvanitidou, Lia S.; Panagakos, Fotinos; Vizio, William De; Zhang, Yun Po; Mateo, Luis R; Yin, Wei

doi:10.1016/j.jdent.2012.10.001

Cited by 24 publications

(35 citation statements)

References 16 publications

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“…Light from an Er, Cr:YSGG laser is absorbed more strongly by OH ions of water molecules if the laser can cause an increase in the surface temperature, and this can hence alter the mineral content of the enamel and the dentin [38]. Freitas, et al recently indicated that low-power laser irradiation from an Er, Cr:YSGG laser at 0.25W or 0.5W allows the surface to become more resistant to acid consequent to changes in the structure of the enamel due to the chemical entities that are produced [13]. These authors hence speculated that Er, Cr:YSGG lasers can reduce DH in the long run due to the prevention of caries and due to effects on the decrease in solubility of the hard dental tissues.…”

Section: Discussionmentioning

confidence: 99%

“…A comparison of an arginine-based mouthwash (0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride) versus a placebo mouthwash without alcohol and without other components has shown that the arginine mouthwash provided a significant reduction in DH after eight weeks of use relative to a negative control mouthwash [13]. Other studies have shown that a toothpaste containing 8% arginine, calcium carbonate, and 1,450 ppm of sodium monofluorophosphate provided a greater efficacy in terms of reducing DH, relative to a desensitizing toothpaste containing 2% potassium ions [43,44].…”

Section: Discussionmentioning

confidence: 99%

“…Analysis of the quality based on CONSORT criteria showed that 10 articles were deemed to have a low risk of bias [6][7][8][9][10][11][12][13][14][15]. Two studies [16,17] were considered to have moderate risks for bias.…”

Section: Extraction Of the Datamentioning

confidence: 99%

“…Lastly, three articles were in regard to the clinical efficacy of Pro-arginine mouthwashes and toothpastes on DH [6,13,22].…”

Section: -Week Periodmentioning

confidence: 99%

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Treatment of Dentin Hypersensitivity: A Systematic Review of Randomized Clinical Trials

F¹,

Niang²,

Faye³

et al. 2016

Journal of Dentistry and Oral Care Medicine

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Extraction Of the Datamentioning

confidence: 99%

“…Lastly, three articles were in regard to the clinical efficacy of Pro-arginine mouthwashes and toothpastes on DH [6,13,22].…”

Section: -Week Periodmentioning

confidence: 99%

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Treatment of Dentin Hypersensitivity: A Systematic Review of Randomized Clinical Trials

F¹,

Niang²,

Faye³

et al. 2016

Journal of Dentistry and Oral Care Medicine

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“…The formulation derived from this combination, Pro-Argin, has been described as a novel occlusion technology based on the fact that 8% arginine and calcium carbonate are believed to seal exposed dentinal tubules with a plug that contains arginine, calcium carbonate and phosphate thereby providing relief for DH [52]. This claim has been supported by the results of studies which demonstrated relief of DH for variable periods following the use of Pro-Argin mouthwash or paste [52,53]. Although previous systematic reviews have recommended arginine-containing toothpastes for treatment of DH [50,51].…”

Section: Recent Developments In the Treatment Of Dentine Hypersensitimentioning

confidence: 99%

Dentine Hypersensitivity: Review of a Common Oral Health Problem

Pi¹,

Asa²,

Mohammed³

et al. 2017

J Den Craniofac Res

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Dentine hypersensitivity remains an enigma. Although, it is known to usually present with sharp, short pain caused by one or more external stimuli, it is often inadequately understood. Controversies therefore abound concerning the appropriate terminology for the condition, variations in prevalence, and what is most important to the patients suffering from the condition -a treatment that provides immediate relief with long lasting effect. Available interventions using desensitizing agents provide only temporary relief. The interest of dental practitioners and researchers in dentine hypersensitivity remains very high as it is still a common complaint among patients globally. The myriad array of treatments available and claims of efficacy has not lessened the clinician's dilemma. As a guide and update for clinicians, the aim of this paper is to review the published literature and provide current opinion on the prevalence, aetiology, mechanism, clinical features, treatment as well as the concept of oral health related quality of life among patients with dentine hypersensitivity. A manual and PubMed literature search was conducted using the keywords: dentine hypersensitivity, tooth sensitivity, cervical dentine hypersensitivity, root dentine hypersensitivity in combination with the words prevalence, epidemiology, diagnosis, mechanism, aetiology, clinical features, treatment, oral health or quality of life. The recently developed treatment agents appear promising but will require more randomized clinical trials. Dentine hypersensitivity remains a common condition with significant effect on daily life. The incorporation of a measure of oral health related quality of life is recommended as one of the outcome measures for new treatment modalities.

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Dentists’ education, knowledge, and professional behavior concerning the diagnosis and treatment of dentin hypersensitivity: An exploration

Agheli,

De Faria Neiva,

Maia

et al. 2023

Journal of Dental Education

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Objectives: Dentin hypersensitivity (DH) affects patients’ oral health‐related quality of life, but is not always optimally treated in dental offices. The objectives were to assess dentists’ DH‐related education, knowledge, and professional behavior and explore relationships between education, knowledge, and behavior.Methods: Survey data were collected from 220 ADA members in the United States. Descriptive and correlational analyses were performed.Results: About half of the respondents agreed/strongly agreed that their dental school had educated them well about diagnosing DH in classroom‐based (53.6%) and clinical settings (48.9%). Lower percentages agreed being well educated about treating DH (40.9%/37.3%). The majority self‐educated themselves about DH after dental school by attending continuing education courses in person or online (60.6%/36.8%), reading articles (64.1%), or consulting with colleagues (59.6%). The majority knew that patients with DH describe their pain as stimulated (91.4%) and that recessed gingiva (89.6%), abrasion lesions (72.3%), tooth whitening (63.1%), erosion lesions (58.6%), and abfraction lesions (51.4%) are risk factors for DH. The majority diagnosed DH with patient self‐reporting, confirmed by exams (81.8%), applying air blasts (53.7%), or cold‐water (52.3%). They treated patients with DH often/very often with over‐the‐counter desensitizing agents (90%), and prescribing fluoride formulations toothpaste (82.8%) and/or potassium nitrate toothpastes (60.9%). In their offices, the majority (73.2%) educated their patients often/very often about DH and used fluoride dental varnish for treating DH (71.8%). The more recently respondents had graduated from dental school, the more positively they described their dental school education (r = 0.14; p < 0.05), the more ways to diagnose DH they used (r = 0.16; p < 0.05) and the more often they used fluoride dental varnish in their offices (r = 0.23; p < 0.001). The more dentists had educated themselves, the more methods for diagnosing DH they used (r = 0.23; p < 0.001) and the more often they used potassium oxalate products (r = 0.19; p < 0.01), Arginine/calcium products (r = 0.19; p < 0.01) and dentin bonding (r = 0.22; p < 0.001).Conclusions: More recently graduating from dental school correlates with more positive evaluations of DH‐related dental school education. The finding that most dentists engage in self‐education about DH after dental school should motivate dental educators to increase education about this topic not only in dental school, but also in continuing education courses.

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Efficacy of a mouthwash containing 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride compared to a negative control mouthwash on dentin hypersensitivity reduction. A randomized clinical trial

Abstract: The results of this study support the conclusion that the Arginine Mouthwash provides a significant reduction in dentin hypersensitivity after eight weeks of product use as compared to a Negative Control mouthwash.

Cited by 24 publications

References 16 publications

Treatment of Dentin Hypersensitivity: A Systematic Review of Randomized Clinical Trials

Treatment of Dentin Hypersensitivity: A Systematic Review of Randomized Clinical Trials

Dentine Hypersensitivity: Review of a Common Oral Health Problem

Dentists’ education, knowledge, and professional behavior concerning the diagnosis and treatment of dentin hypersensitivity: An exploration

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