Dear Editor,We read the recent article by Agheli et al. 1 with great interest. The authors highlight that Dentin Hypersensitivity (DH) affects patients' oral health-related quality of life and conclude that more efforts are needed to educate future dentists more optimally about diagnosing and treating DH. 1 As caregivers and oral health professionals in a Cancer Center, we are particularly aware of the degradation of the oral condition and the impact on patients' oral quality of life induced by oncologic treatments and notably radiation therapy. According to Pinna et al. 2 and in line with our practice, radiation-treated head and neck cancer patients with hyposalivation may be a new risk group for DH that should be known by educators. Radiation therapy frequently leads to reduced salivary flow (depending on the dose and fields of radiation) and can severely affect soft and hard oral tissues included the development of DH. [3][4][5] For these patients, the management of DH starts by preventive strategy as the maintain of oral hygiene during radiotherapy which can lead to gingival recession related dental exposure. 5 At the Institut Universitaire du Cancer de Toulouse-Oncopole, our oral medicine team, dedicated to supportive care, sets up regular followups to assess oncologic treatments related oral toxicities, oral hygiene and pain during radiation therapy. From our observations, caregivers play a significant role in the management of cancer patients by helping them to maintain meticulous oral hygiene during treatments. Patients are monitored weekly or even daily by the caregiver, depending on oral pain or discomfort. Once the treatment is achieved, we follow up patients during 1 at 2 years to prevent notably dental complications. Concerning noninvasive treatments for DH, our team apply desensitizing products who leads to a reduction in symptoms to the levels in irradiated xerostomic patients. The application of desensitizing agents coupled with fluoride in varnish form is particularly interesting for the management of irradiated patients. It is important to be able to offer simple, rapid therapies for these patients, and to maintain regular follow-up every 3 months. The management of irradiated patients is unfortunately underdeveloped in dental school and continuing education courses. The pain caused by DH impairs patients' quality of life. We suggest that a standard protocol for this DH risk group patient should be developed by dental educators, included the role of caregivers to maintain oral hygiene during radiation therapy.