“…Significantly, no cross-resistance was observed between Pyridalyl and various currently used insecticides in Plutella xylostella or Heliothis virescens (Sakamoto et al, 2003). Pyridalyl exhibited an LD50 value against various Lepidoptera in the range of 0.77e4.48 ppm (Saito et al, 2002), that is mostly in the same range as for other insecticides (0.1e4.2, or 0.1e2800 ppm) (Pasquier and Charmillot, 2003;Ioriatti et al, 2006), depending on species, developmental stage, method of application, and compound used. Treatment of Spodoptera litura larvae with 25 ng/larva or lower caused unique symptoms after moulting, similar to scar burns at the site of treatment, that caused interference with metamorphosis (Saito et al, 2004).…”