Efficacy and Tolerance of Trandolapril (0.5–2 mg) Administered for 4 Weeks in Patients with Mild-to-Moderate Hypertension

Brazilian multicenter study on efficacy and tolerability of trandolapril in mild-to-moderate essential arterial hypertension. EMBATHE substudy with ambulatory blood pressure monitoring

“…Even with relatively low doses such as 2.0mg/day, normalization or satisfactory blood pressure reduction e.g. a 10mmHg reduction in BP occurs in about 70% of patients, as demonstrated by many studies with distinct follow-up periods 2,3 . Furthermore, the antihypertensive efficacy of this drug over placebo 2,4 and similar to that of many other antihypertensive compounds 5 has been clearly demonstrated by several studies.…”