Efficacy and safety of the combined use of ipilimumab and nivolumab for melanoma patients with brain metastases: a systematic review and meta-analysis

Brain metastases: Comparing clinical radiological differences in patients with lung and breast cancers treated with surgery

“…BMs from lung and breast cancer are the most frequent types of secondary intracranial lesions in adults since melanoma patients were nowadays excluded as they have seen significant progress in the development of systemic therapies to improve control of the primary disease, reducing the percentage who develop BM. 20 , 21 , 22 , 23 Biologically and prognostically, the two types cannot be comparable since they are two different clinical entities, but at the time of acute clinical onset where there is radiological evidence of a surgically treatable contrast capturing lesion their appearance can be very similar and difficult to distinguish to other tumors ( Fig. 7 ).…”