Efficacy and safety of long pulse 1064 and 2940 nm lasers in noninvasive lipolysis and skin tightening

Vas, Krisztina; Besenyi, Zsuzsanna; Urbán, Szabolcs; Badawi, Ashraf; Pajor, László; Erős, Gábor; Kemény, Lajos

doi:10.1002/jbio.201900083

Cited by 15 publications

(11 citation statements)

References 29 publications

(27 reference statements)

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“…Improved wrinkle appearance that was evident from the results of our study could be attributed to improved skin elasticity, which has previously been proved to be achieved using the same SMOOTH™ laser modality [35].…”

supporting

confidence: 72%

Periocular rejuvenation using a unique non-ablative long-pulse 2940 nm Er:YAG laser

Badawi

Sobeih

Jasmina³

2021

Lasers Med Sci

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The periocular region is challenging for cosmetic laser surgeons. Surgery and laser resurfacing have traditionally been used to correct periorbital lines and wrinkles. Although effective, the associated downtime with these methods has made many people reluctant to decide for such treatments. More recently, the non-ablative long-pulse 2940 nm Er:YAG laser is being used to improve the structure and function and hence the appearance of skin in the periorbital region. The objective of this study is to evaluate the safety and efficacy of long-pulse 2940 nm Er:YAG laser for non-ablative treatment of periorbital static wrinkles and skin laxity. This is a prospective analysis of 30 patients treated for periorbital rejuvenation using three sessions of non-ablative long-pulse Er:YAG laser over a 3-month period. All patients were assessed according to Fitzpatrick’s classification of periorbital wrinkles to class I, II, or III and were treated with 2940 nm Er:YAG laser using a fluence of 3.75 J/cm2, a repetition rate of 1.7–2 Hz, and with the SMOOTH™ pulse mode (250 ms). The treatment sessions were performed on each patient, 4 weeks apart. Patient improvement was assessed before each laser session as well as at 12 months after the final treatment. Blind photographic evaluations were performed by three independent physicians using unlabeled before and after photos arranged in non-chronological order. Reviewers were asked to determine the before and after photos. Patients were asked to answer a questionnaire measuring satisfaction 4 weeks after each session, and to report any adverse reactions. There was statistically and clinically significant improvement in the Fitzpatrick classification of the periorbital wrinkles. Blinded evaluators correctly identified the before and after photos in all cases. All patients reported mild edema and erythema, which persisted for 1 to 2 days, and superficial peeling of the skin for 4 to 6 days after each laser treatment. No long-term adverse effects were reported. The non-ablative long-pulse 2940 nm Er:YAG laser seems to be a safe and effective treatment for periocular rejuvenation with minimal and tolerable adverse reaction. The improvement attained from the laser sessions was persisting after 1 year denoting the long-term efficacy of the procedure.

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supporting

confidence: 72%

Periocular rejuvenation using a unique non-ablative long-pulse 2940 nm Er:YAG laser

Badawi

Sobeih

Jasmina³

2021

Lasers Med Sci

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“…A máj vizsgálata tekintetében említésre méltó, hogy az elasztográfia mint vizsgálómódszer szerepel a hepatitis B-és D-vírus-fertőzés diagnosztikájával foglalkozó hazai konszenzusajánlásban, valamint egyik alapvető vizsgálóeljárása a májat érintő klinikai kutatásoknak [7,8]. Szintén hazai közlemények húzzák alá az UHE lehetséges szerepét az emlőrák diagnosztikájában, de bőrgyógyászati és colorectalis alkalmazásáról is olvashatók folyóiratcikkek [9][10][11]. Az UHE egyre növekvő számú közleménnyel alátámasztva mindinkább szerepet kap a szülészeti-nőgyógyászati betegségek és állapotok diagnosztizálásában is.…”

Section: öSszefoglaló Közleményunclassified

Ultrahang-elasztográfia alkalmazásának lehetőségei a szülészet-nőgyógyászatban

Kozma

Pákozdy

Lampé

et al. 2021

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Összefoglaló. Az ultrahang-elasztográfia az elmúlt évek során egyre növekvő figyelmet kapott a lágyszövetek elaszticitásának vizsgálatában. A módszer használatát az teszi szükségessé, hogy egyes, a mechanikai tulajdonságaikban különböző szövetek hasonló echogenitásúak lehetnek, valamint hogy egy adott szövet megváltozott struktúrája vagy mechanikai tulajdonsága nem minden esetben jár együtt a szövet hagyományos ultrahangképének megváltozásával. Az elmúlt évtizedben a deformációs és a nyírási ultrahang-elasztográfia vált széles körben elérhetővé. Ezen új képalkotási technika egyre nagyobb szerepet tölt be a szülészeti-nőgyógyászati ultrahang-diagnosztikában is. A nőgyógyászatban szerephez juthat az endometriosis és az adenomyosis kimutatásában, valamint a benignus és a malignus cervicalis és ovarialis képletek elkülönítésében. A nőgyógyászathoz hasonlóan a szülészetben is jelentős változást hozhat az ultrahang-elasztográfia: alkalmas lehet a szülésindukció sikerességének, a koraszülés bekövetkezésének és a praeeclampsia kialakulásának előrejelzésére. Orv Hetil. 2021; 162(18): 690–695. Summary. Ultrasound elastography has received significant attention for the assessment and measurement of soft tissue elastic properties in recent years. The advantage of ultrasound elastography lies in the fact that two different tissues can share similar echogenicities but may have other mechanical properties or, on the contrary, mechanical abnormalities of a designated tissue do not necessarily go hand in hand with an altered appearance on a conventional ultrasound image. In the last decade, strain and shear-wave elasticity imaging methods have become the most widely available among commercial ultrasound equipments. The importance of this new method expands rapidly also in the field of obstetrics and gynecology. Ultrasound elastography has a promising role in the diagnosis of endometriosis and adenomyosis and helps to differentiate benign and malignant cervical and ovarian lesions. The use in the prediction of the outcome of labor induction and preterm birth, and in the evaluation of preeclampsia are emerging. Orv Hetil. 2021; 162(18): 690–695.

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“…In some literature reports, PBM is associated with aerobic or resistance exercise, while other reports have mentioned waist and arm circumference reductions with the use of PBM, displaying an absence of diet restrictions or exercise requirements. [25][26][27][28][29] It is also reported that the amount of fat mobilised during a PBM session is similar to the amount that is consumed during a meal, in such a way that it can be absorbed by normal body energy requirements (and/or exercise routine), while at the same time, the risk of atherosclerosis is not increased by the treatment. 30 On the other hand, if not consumed, these fatty acids may be re-esterified and redistributed throughout the body, 30 causing no final changes in waist circumference.…”

Section: Open Accessmentioning

confidence: 99%

Study protocol for the use of photobiomodulation with red or infrared LED on waist circumference reduction: a randomised, double-blind clinical trial

et al. 2020

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IntroductionThe search for non-invasive procedures to reduce localised adiposity in aesthetics clinics has recently been increasing. In this context, procedures, such as cryolipolysis, ultracavitation, photobiomodulation (PBM) and other techniques have been proposed. Some studies have shown that PBM can be used in body contouring. However, there is no standardisation of the protocol. More than that, as in other techniques for reducing adipose tissue, the availability of triacylglycerol may affect the lipid profile in the blood, bringing consequences to the general health of an individual. This work will aim to compare the light wavelengths when using PBM as a technique for reducing the abdominal waist circumference, while also evaluating the efficacy of the method. Changes in the lipid profile in the blood, with a long-term follow-up, will also be appraised.Methods and analysisThis will be a controlled, randomised, double-blind, single-centred clinical trial. 174 patients will be recruited at the Nove de Julho University, Brazil, and then divided into three groups: Group A—RED PBM; Group B—INFRARED PBM; Group C—PLACEBO (Sham) treatment. The treatments will consist of eight sessions, two times a week, for 4 weeks. At each session, the participants will receive 30 minutes PBM (using a radiant exposure of 127 J/cm2), with an abdominal strap containing 4 LED clusters, with 72 devices each, following the indication of randomisation. All of the groups will receive 30 min of Aussie Current, at 4 kHz, modulated at 10 Hz, 40–60 mA. The main outcome of this study will be waist circumference reduction. The secondary variables will be anthropometric data, lipid profile, liver function and adipose tissue thickness, changes in the local microcirculation, and the quality of life and self-esteem. The analyses will be performed at four stages of the research, D0, end of the eighth session (D30), 15 days after the last session (FU15), 90 days after the last session (FU90) and 180 days after the last session (FU180).Ethics and disseminationThe Ethics Committee of the Nove de Julho University, Brazil, approved the modified version of this project under No. 3414146 on 26 June 2019. This study is not yet recruiting. The results obtained will be published in a peer-reviewed journal in the related field.Trial registration numberBrazilian Registry of Clinical Trials—ReBec (RBR-9bwxcx).

show abstract

Efficacy and safety of long pulse 1064 and 2940 nm lasers in noninvasive lipolysis and skin tightening

Cited by 15 publications

References 29 publications

Periocular rejuvenation using a unique non-ablative long-pulse 2940 nm Er:YAG laser

Periocular rejuvenation using a unique non-ablative long-pulse 2940 nm Er:YAG laser

Ultrahang-elasztográfia alkalmazásának lehetőségei a szülészet-nőgyógyászatban

Study protocol for the use of photobiomodulation with red or infrared LED on waist circumference reduction: a randomised, double-blind clinical trial

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