Efficacy and safety of freeze-dried form of <i>Tragia involucrata</i> L. decoction in treating diabetes: a randomized controlled clinical trial

Pallie, M. S.; Perera, Pathirage Kamal; Goonasekara, Charitha L.; Kumarasinghe, Nishantha; Arawwawala, Menuka

doi:10.4103/2542-3975.300614

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The antioxidant activity of Tragia spp. extracts underlie several ethnopharmacological uses which have been validated in vivo and have undergone clinical trials [76][77][78].…”

Section: Compoundsmentioning

confidence: 99%

Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract

Romero-Benavides,

Atiencie-Valarezo,

Duarte-Casar

2023

Plants

View full text Add to dashboard Cite

Several species from the genus Tragia L. in the family Euphorbiaceae are part of the ethnomedicine of traditional cultures, and have a variety of uses. Tragia volubilis L. is a species spread through tropical America and Africa with several ethnomedical uses, particularly for wound healing and reproductive issues. In this study, we assess the phytochemical composition and antioxidant activity of the methanolic extract of the aerial parts of T. volubilis collected in southern Ecuador. The phytochemical screening of the extract shows the preliminary presence of carbohydrates, alkaloids, flavonoids, and tannins. The extract shows an Antioxidant Activity Index of 1.14, interpreted as strong antioxidant activity. Four flavonoid compounds were isolated through chromatographic procedures and identified through NMR spectroscopy: avicularin, quercitrin, afzelin, and amentoflavone. The biological activity of these compounds matches the ethnopharmacological uses of the species. This is the first phytochemical study of T. volubilis and supports its traditional medicinal uses.

show abstract

“…The antioxidant activity of Tragia spp. extracts underlie several ethnopharmacological uses which have been validated in vivo and have undergone clinical trials [76][77][78].…”

Section: Compoundsmentioning

confidence: 99%

Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract

Romero-Benavides,

Atiencie-Valarezo,

Duarte-Casar

2023

Plants

View full text Add to dashboard Cite

show abstract

Tragia L. Genus: Ethnopharmacological Use, Phytochemical Composition and Biological Activity

Duarte-Casar

Romero-Benavides

2021

Plants

View full text Add to dashboard Cite

Tragia L. is a genus of plants belonging to the Euphorbiaceae family with worldwide intertropical distribution, composed of more than 150 species. In this literature review, 26 species of the genus used as medicinal plants were found, mainly in East Africa and the Indian subcontinent, with a variety of uses among which antibacterial, anti-inflammatory, anticancer and reproductive health are most common. Research has been done on a few of the species, mostly those of the Old World, with emphasis on four of them: Tragia involucrata Linn., Tragia spathulata Benth., Tragia benthamii Baker and Tragia plukenetii Radcl.-Sm., confirming several ethnomedicinal claims. Moreover, a variety of active phytochemicals have been isolated, mainly ethers, hydrocarbons, flavonoids and sterols. There is ample field for the evaluation of the activity of Tragia extracts and essential oils and the identification of their active compounds, particularly of the New World species, for which there is still very little research.

show abstract

Efficacy and safety of freeze-dried form of Tragia involucrata L. decoction in treating diabetes: a randomized controlled clinical trial

Cited by 2 publications

References 0 publications

Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract

Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract

Tragia L. Genus: Ethnopharmacological Use, Phytochemical Composition and Biological Activity

Contact Info

Product

Resources

About