Efficacy and safety of enucleation vs. resection of prostate for treatment of benign prostatic hyperplasia: a meta-analysis of randomized controlled trials

Impact on Sexual Function of Endoscopic Enucleation vs Transurethral Resection of the Prostate for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis

“…14 In recent years, EEP has been developed and recognized as a viable treatment option due to reduced morbidity and shorter convalescence. [11][12][13] The basic procedure of enucleation is removing adenoma of prostate along the surgical capsule plane with less heating effect and vascular injury, so EEP was considered of potential benefit to preserving the sexual function. 8,10 Marginal and nonsignificant EF improvement was reported in the analyses of 12-and 24-month post-HoLEP IIEF scores, 19,30 and in the 12-month follow-up evaluation after ThuVEP.…”

“…10 There were several meta-analyses on the direct comparison of the efficacy and safety of transurethral enucleation and resection of prostate for LUTS due to BPH, but few of them focused the treatment impact on erectile function (EF) or ejaculation function (EJF). [11][12][13] One such systematic review and network meta-analysis compared the International Index of Erectile Function 5 (IIEF-5) scores after different surgical treatments for LUTS/BPH, but it did not evaluate EJF, which is also an important component of overall sexual function. 14 In another earlier meta-analysis, including comparison of the impact on EF or EJF between TURP and holmium laser treatment, the recently developed methods of EEP such as thulium laser enucleation or PKEP were not included.…”

Complications of anatomical endoscopic enucleation of the prostate

“…Recently, a high‐quality meta‐analysis of RCTs involving 26 RCTs with 3,283 patients also revealed that there was no significant difference in the overall occurrence rate of post‐operative urge UI or stress UI between AEEP and TURP (Zhang, Ou, et al, ; Zhang et al, ). However, Luo, Shen, Guan, Li, and Wang () found that UI rate of BipoLEP was significantly higher than plasmakinetic resection of the prostate (PKRP) (17.1% vs. 5.8%, p = .002).…”

“…It is believed that AEEP will become the ‘future standard’ instead of TURP for BPO surgical treatment (Naspro et al, ). However, perioperative complications of AEEP is inevitable although the incidence is lower compared with TURP and open prostatectomy (OP) (Elshal et al, ; Yin et al, ; Zhang et al, ). There were few studies reviewing the surgical complications of AEEP.…”

Prostate Cancer and Prostatic Diseases Best of Asia, 2019: challenges and opportunities

“…8. Efficacy and safety of enucleation vs. resection of prostate for treatment of benign prostatic hyperplasia: a meta-analysis of randomized controlled trials [10]. Authors indicate that enucleation has better efficacy and safety postoperatively with less hematological changes and severe complications, compared with resection in treating benign prostatic hyperplasia.…”