2021
DOI: 10.3390/ani11113254
|View full text |Cite
|
Sign up to set email alerts
|

Efficacy and Safety of Dexmedetomidine Premedication in Balanced Anesthesia: A Systematic Review and Meta-Analysis in Dogs

Abstract: Dexmedetomidine is commonly used in small animal anesthesia for its potent sedative and analgesic properties; however, concerns regarding its cardiovascular effects prevent its full adoption into veterinary clinical practice. This meta-analysis was to determine the effects of dexmedetomidine on sedation, analgesia, cardiovascular and adverse reactions in dogs compared to other premedications. Following the study protocol based on the Cochrane Review Methods, thirteen studies were included in this meta-analysis… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

4
14
0
1

Year Published

2022
2022
2023
2023

Publication Types

Select...
6
1
1

Relationship

0
8

Authors

Journals

citations
Cited by 17 publications
(19 citation statements)
references
References 42 publications
4
14
0
1
Order By: Relevance
“…This was consistent with research results of Jiang et al (2017) [30]. Pan et al (2021) [31] presented that Dex had satisfactory sedative and analgesic effects and the incidence of adverse reactions was 0.47%.…”
Section: Resultssupporting
confidence: 91%
“…This was consistent with research results of Jiang et al (2017) [30]. Pan et al (2021) [31] presented that Dex had satisfactory sedative and analgesic effects and the incidence of adverse reactions was 0.47%.…”
Section: Resultssupporting
confidence: 91%
“…The combination of alpha-2 agonists and ketamine leads to a more reliable, steady, and profound sedation than alpha-2 agonists alone [14][15][16][17]. Ketamine is a dissociative agent able to provoke a dosedependent loss of consciousness while maintaining re exes, such as the swallowing re ex [18].…”
Section: Introductionmentioning
confidence: 99%
“…Dexmedetomidine, an α2 adrenergic agonist, has been used widely in domestic and exotic animals including wildlife, dogs [ 5 , 6 ], cats [ 7 ], rodents [ 8 , 9 ], dairy and dromedary calves [ 10 , 11 ], horses [ 12 ], miniature donkeys [ 13 ], and captive tigers [ 14 ]. Like other α2 adrenergic agonists, it provides sedation, muscle relaxation, and analgesia [ 15 ]; there- fore, it has gained popularity over the last 10 years.…”
Section: Introductionmentioning
confidence: 99%