Efficacy and safety of 1927 nm fractional Thulium fiber laser for the treatment of melasma: a retrospective study of 100 patients

Kurmuş, Gökçe Işıl; Tatlıparmak, Aslı; Aksoy, Berna; Koç, Erol; Serdar, Zehra Aşiran; Ergin, Can

doi:10.1080/14764172.2019.1683581

Cited by 10 publications

(10 citation statements)

References 18 publications

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“…Most studies regarding 1927 nm fractional TFL have focused on the treatment of melasma and PIH, suggesting it is a safe and effective treatment option [7,17,18]. In particular, in PIH treatment, whose pathogenesis and histologic features are similar to Riehl's melanosis, TFL was reported to show a promising effect.…”

Section: Discussionmentioning

confidence: 99%

Non‐Ablative 1927 nm Fractional Thulium Fiber Laser: New, Promising Treatment Modality for Riehl's Melanosis

et al. 2020

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Background and Objectives: The treatment of Riehl's melanosis, also known as pigmented contact dermatitis, is highly challenging. Intense pulsed light (IPL) and 1064 nm Q-switched Nd:Yag (QS-Nd:YAG) laser are reported to have some efficacy. However, no single effective treatment has yet been identified. In this study, we demonstrated the efficacy and safety of the non-ablative 1927 nm fractional thulium fiber laser (TFL, LASEMD™; Lutronic Corp., Goyang, Korea) for patients with Riehl's melanosis. Study Design/Materials and Methods: A retrospective chart and photographic review of nine patients with Riehl's melanosis, who had received at least three sessions of TFL treatment, was performed. Before the start of TFL treatment, combination treatment with a topical cream containing hydroquinone, low-fluence QS-Nd:YAG laser, pulsed dye laser, and IPL was used with variable and discouraging effects. Seven patients were treated on the face and two patients on the neck with three to seven sessions at 1-month intervals. Clinical improvement was assessed using clinical photos taken before and after every treatment session according to dermal pigmentation area and severity index (DPASI) and a quartile grading scale by two blinded dermatologists. Results: Patients underwent three to seven sessions of TFL treatment depending on severity of pigmentation. Of nine patients, six demonstrated a clinical improvement of 51%-75%, one demonstrated an improvement of 76%-100%, and two showed an improvement of 26%-50% after treatment. The DPASI was significantly decreased from 9.55 to 5.25 on average. Melanin index was decreased after treatment in two patients whose melanin index were measured at initial visits. Treatment-related adverse events, such as scarring or postinflammatory hyperpigmentation (PIH), were not observed in all patients except for transient erythema and swelling. Conclusions: This report suggests that TFL could be an alternative and/or additive treatment option for hyperpigmentation in intractable Riehl's melanosis and might be a promising treatment for PIH caused by any reason including Riehl's melanosis. Lasers Surg. Med.

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Section: Discussionmentioning

confidence: 99%

Non‐Ablative 1927 nm Fractional Thulium Fiber Laser: New, Promising Treatment Modality for Riehl's Melanosis

et al. 2020

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“…18 At all time points analyzed (1, 2, and 6 months), the mean Melasma Area and Severity Index (MASI) score was significantly improved (p , .005 for all). 18 Three percent of patients experienced PIH, and 2% of patients had reoccurrence of melasma. 18 In the other study, 20 women (mean age, 41.1 years [range, 30-51 years]) with FST II to IV underwent 1 treatment with the 1,927 nm laser (10 or 20 mJ/cm 2 [60%-70% coverage]).…”

Section: 927 Nm Thulium Lasermentioning

confidence: 91%

“… 18 Three percent of patients experienced PIH, and 2% of patients had reoccurrence of melasma. 18 In the other study, 20 women (mean age, 41.1 years [range, 30–51 years]) with FST II to IV underwent 1 treatment with the 1,927 nm laser (10 or 20 mJ/cm 2 [60%–70% coverage]). 19 Patients were advised to initiate treatment with topical hydroquinone 4.0% 1 month after the procedure.…”

Section: Methodsmentioning

confidence: 97%

“…Two retrospective analyses have been published on treatment with the 1,927 nm laser for melasma. 18 , 19 In one study, 100 patients (mean age, 37.8 years [range, 19.0–57.0 years]) with FST II to V underwent 2 treatments with the 1,927 nm laser (9–10 mJ [30%–50% coverage]; delivered over 3 passes) at 4-week intervals. 18 At all time points analyzed (1, 2, and 6 months), the mean Melasma Area and Severity Index (MASI) score was significantly improved ( p < .005 for all).…”

Section: Methodsmentioning

confidence: 99%

“… 18 , 19 In one study, 100 patients (mean age, 37.8 years [range, 19.0–57.0 years]) with FST II to V underwent 2 treatments with the 1,927 nm laser (9–10 mJ [30%–50% coverage]; delivered over 3 passes) at 4-week intervals. 18 At all time points analyzed (1, 2, and 6 months), the mean Melasma Area and Severity Index (MASI) score was significantly improved ( p < .005 for all). 18 Three percent of patients experienced PIH, and 2% of patients had reoccurrence of melasma.…”

Section: Methodsmentioning

confidence: 99%

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1,550 nm Erbium-Doped and 1,927 nm Thulium Nonablative Fractional Laser System: Best Practices and Treatment Setting Recommendations

Friedman

Dover

Chapas

et al. 2022

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BACKGROUND The Fraxel Dual laser system (Solta Medical, Inc., Bothell, WA) contains a 1,550 and 1,927 nm wavelength single handpiece with different indications for each wavelength. OBJECTIVE To discuss treatment setting recommendations and best practices for select on-label and investigational applications of the 1,550 and 1,927 nm dual laser system. MATERIALS AND METHODS Eight board-certified dermatologists with 10 or more years of experience with the 1,550 and 1,927 nm laser system completed an online survey about their clinical experience with the system and then participated in a roundtable to share clinical perspectives and best practices for using the laser system. RESULTS For all Fitzpatrick skin types, treatment recommendations were described for selected approved indications for the 1,550 and 1,927 nm laser system, including both lasers in combination. Treatment recommendations were also reached for investigational applications with the 1,550 nm laser and 1,927 nm laser. Best practices for using the lasers during the treatment session to achieve optimal outcomes and decrease the post-treatment recovery time were compiled. CONCLUSION The 1,550 and 1,927 nm dual laser system is effective for a wide range of aesthetic and therapeutic applications, on and off the face and across all Fitzpatrick skin types.

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Non‐ablative Lasers

Kesty

Goldberg

2022

Cosmetic Dermatology

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Efficacy and safety of 1927 nm fractional Thulium fiber laser for the treatment of melasma: a retrospective study of 100 patients

Cited by 10 publications

References 18 publications

Non‐Ablative 1927 nm Fractional Thulium Fiber Laser: New, Promising Treatment Modality for Riehl's Melanosis

Non‐Ablative 1927 nm Fractional Thulium Fiber Laser: New, Promising Treatment Modality for Riehl's Melanosis

1,550 nm Erbium-Doped and 1,927 nm Thulium Nonablative Fractional Laser System: Best Practices and Treatment Setting Recommendations

Non‐ablative Lasers

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