BACKGROUND
AbobotulinumtoxinA has been investigated for applications beyond facial rhytides, including the treatment of oily skin.
OBJECTIVE
The authors sought to investigate the optimal number of units and the duration of abobotulinumtoxinA for the treatment of oily skin.
MATERIALS AND METHODS
This randomized, double-blinded, placebo-controlled study included 50 male and female subjects that got either 0, 15, 30, or 45 units of abobotulinumtoxinA injected into their forehead. For the 6 months after treatment, subjects were evaluated for the effectiveness of the treatment in decreasing the oiliness of their skin and the duration of this effect.
RESULTS
Subjects in the treatment groups that received either 30 or 45 units of neurotoxin experienced a significant reduction in oily skin. This effect was present for the 6-month duration of the study. No treatment-related adverse events were reported during this study, and both subjects and investigators reported a high level of satisfaction with the treatment.
CONCLUSION
Thirty or 45 units of abobotulinumtoxinA are safe and effective doses in treating oily skin for improved cosmetic appearance.
BackgroundA variety of energy‐based devices have been used to treat acne. However, all studies have been subjective and have not involved double‐blind and randomized controlled studies.AimsWe undertook a randomized controlled study evaluating the use of a 650 usec 1064 nm Nd:YAG laser compared with a sham in the treatment of acne.Patients/MethodsA total of 20 subjects with moderate‐to‐severe acne were randomized to receive either 650 usec 1064nm Nd:YAG laser or sham treatment. All subjects received 3 treatments, two weeks apart, plus an additional session undertaken 4 weeks after the 3rd treatment. Subjects were evaluated for investigator global improvement, improvement in inflammatory lesions, improvement in comedonal lesions, total porphyrin score, and total sebum score.ResultsThe laser‐treated group showed an Investigator's Global Assessment Scale (IGA) improvement of 26% compared with 7% for the sham group (a 271% improvement over sham treatment group). The treatment group also showed a decrease in the number of inflammatory lesions of 42% compared with 26% in the sham group (a 62% improvement over sham). The laser‐treated cohort also experienced a reduction in total number of comedones similar to that seen with inflammatory lesions and a decrease in total porphyrin score. There was also an 18% reduction in sebum production in the treated group, compared with 9% in the sham group (a 100% improvement).ConclusionThis is the first study that has compared laser treatment of acne compared with a sham treatment. A 650 usec 1064nm Nd:YAG laser can effectively treat acne.
Disclosure:The views expressed in the submitted article belong to the authors and are not an official position of the institution or funder. Subjects signed consents allowing their photographs to be used.
AbstractBackground: We have employed radiofrequency microneedling devices in our practice with favorable patient results. Rejuvenation, acne, acne scars, and skin laxity are the most common concerns that we treat with radiofrequency microneedling devices. Patient selection, preparation, and post-procedure follow up can improve clinical outcomes and safety while increasing patient satisfaction.Aims: The purpose of this review is to highlight radiofrequency microneedling methods and present our clinical experience.
Materials and Methods:Articles from PubMed are highlighted and our clinical experience is presented.Results: Radiofrequency microneedling is a safe and effective treatment for acne scars, hyperhidrosis, rosacea, skin laxity and skin rejuvenation and is a key device for any cosmetic dermatologist.Discussion: Dermatologists should consider adding radiofrequency microneedling devices to their treatments offered to patients for a variety of indications.
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