Effects on Metabolism Produced by the Rate of Ingestion of the Diet

Cohn, Clarence; Joseph, Dorothy

doi:10.1093/ajcn/8.5.682

Cited by 115 publications

(14 citation statements)

References 14 publications

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“…The researchers believe that the metabolic load of each cell in the human being, when divided and distributed, can be handled better leading to a more efficient metabolism. Laboratory studies proved that the amount of food obtained by cells can regulate the metabolism process (COHN;JOSEPH, 1960). Instead of imposing a great amount of enzyme activities during digestion, it would be better to reduce the amount of food received by cell, i.e.…”

Section: Methodsmentioning

confidence: 99%

“…Instead of imposing a great amount of enzyme activities during digestion, it would be better to reduce the amount of food received by cell, i.e. reducing the calorie received per meal without cutting short any calorie amount from the whole food during a day thereby reducing the metabolic pressure on cells (COHN;JOSEPH, 1960). In another study, the effect of increasing the number of meals and reducing the amount on type 2 diabetes in order to establish a model for reducing the absorption of nutrients per time unit was studied.…”

Section: Methodsmentioning

confidence: 99%

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The effect of a diet education with six iso-caloric meals on the body weight and blood glucose of diabetes type 2 patients

2012

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The treatment of Diabetes should not only be sought through drug administration; diet is also a part of its treatment. The aim of this study was to determine the effect of a diet with six meals having equal calories on the body weight and blood glucose on diabetes type 2 patients. This research is an Experimental study conducted in 2009 on 181 patients with diabetes. The patients visited the IDSF (Iranian Diabetes Society of Fars) weekly and the patients to be studied were randomly divided into two groups of 85 and 96 patients, respectively. The participants were repeatedly requested to consume their calculated calorie in six equal parts. The average age in the Experimental and Control groups were 51.2 ± 13.3 and 53.1 ± 9.4, respectively. The mean body weight and fasting blood glucose at the beginning of the study in Experimental and Control groups were 66.3 ± 9.4 and 69.1 ± 11.1 kg, 198.9 ± 35.1, and 199.8 ± 39.1 mg.dL-1, respectively. At the end of the study, however, the values were 63.5 ± 7.5 and 66.98 ± 9 kg, 139.5 ± 34.6 and 164.2 ± 22.1 mg.dL-1, respectively. Only the mean fasting blood glucose at the end of the study revealed a significant difference (p-value = 0.001). The results show that educating those afflicted with Diabetes Type 2 aiming at changing their diet can greatly help them manage their blood glucose.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

The effect of a diet education with six iso-caloric meals on the body weight and blood glucose of diabetes type 2 patients

2012

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“…Two models for inducing obesity have been found useful: intragastric feeding (Cohn & Joseph, 1960) and 'cafeteria' feeding (Sclafani & Springer, 1976). Table 2 illustrates the point that the physiological response to intragastric feeding is dependent on the nature of the diet fed .…”

Section: Animal Models For the Study Of Human Nutrition The Concept Omentioning

confidence: 99%

Animal models for the study of energy balance

Gurr

1980

Proc. Nutr. Soc.

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Dairying, University of Reading, Shinfield, Reading RG2 @T The most obvious outcome of the failure to regulate energy balance effectively in animals and man is obesity. To learn how obesity arises and may be prevented, we must understand how animals regulate energy balance or metabolism, but a concentration on obesity as such may focus too much research attention on the adipose tissue, a proliferation of which is the outward sign of a tendency towards positive energy balance though not necessarily the cause of it.Rather than attempting a complete review, I shall select several current areas of research to illustrate specific points in connexion with the question: why do we need 'models'? The concept of energy balanceAn animal is said to be in energy balance when his body energy stores remain constant. His energy intake (metabolizable energy of food) then equals his energy expenditure (total heat output). Energy balance is positive if intake exceeds output; negative if output exceeds input. E,, -Eow = A body energy At least two terms in the equation should be measured. This is accomplished more simply and with greater accuracy over longer periods with animals than with man: a compelling reason for studying animal models to understand basic mechanisms. Changes in body energy are quite difficult to assess properly in man. Deposition of adipose tissue is associated with increases in protein and water as well as fat. Changes in carcass energy can be measured accurately in animals by direct chemical analysis, but it is surprising how frequently this is omitted. It is common for authors to refer only to weight gain as though this can fully describe a change in energy balance. Energy balance can change quite dramatically without any change in weight as illustrated by an example from our work with piglets (Gurr et al. 1980). A group of piglets was fed on a diet of low-protein content (approximately 2% of metabolizable energy) ad lib. The protein level was adjusted so that animals maintained weight. A second group was fed on a high-protein diet

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“…Work performed in recent years revealed that, in addition to the composition of the diet and its calorie value, the frequency of food intake plays an important part in the regulation of metabolic processes (Tepperman, Brobeck & Long, 1943 ;Tepperman & Tepperman, 1958, 1964Cohn &Joseph, 1960;Fibry, 1967a, 6). The laboratory rat is basically a 'nibbler' and, if food is readily available, eats more or less continuously.…”

mentioning

confidence: 99%

“…The original 'nibbler' thus becomes a 'gorger', though the total food intake may even be reduced, as the rat usually does not fully compensate for the periods of food deprivation. Another experimental approach to the study of the effect of large and infrequent loads of food is the use of force-feeding (gavage) (Cohn & Joseph, 1960).…”

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confidence: 99%

Adaptation to the pattern of food intake: some mechanisms and consequences

Fabryand¹,

Braun²

1967

Proc. Nutr. Soc.

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I44 SYMPOSIUM PROCEEDINGS I967or father. He is followed by the other productive members of the family, i.e. the elder sons and younger brothers. Other older children come next and often the mothers and toddlers are last to be considered. Obviously a programme aimed at the toddler will fail if the type of food it receives is acceptable to the other members of the family, unless there is enough for all.T h e animal husbandman is being faced with rising costs all round and a shorter working week. He generally tries to find cheap sources of energy and protein and dietary regimes which will give a considerable concentration of these per unit dry weight. He also wishes to cash in on the most efficient periods of growth and other productions in respect of nutrient utilization. He tries to find labour-saving devices -including changes in dietary pattern-particularly at weekends, but you will hear more about all this from the experts who are with us today.

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Effects on Metabolism Produced by the Rate of Ingestion of the Diet

Cited by 115 publications

References 14 publications

The effect of a diet education with six iso-caloric meals on the body weight and blood glucose of diabetes type 2 patients

The effect of a diet education with six iso-caloric meals on the body weight and blood glucose of diabetes type 2 patients

Animal models for the study of energy balance

Adaptation to the pattern of food intake: some mechanisms and consequences

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