Effects on cardiovascular risk factors of weight losses limited to 5–10 %

Brown, Joshua D.; Buscemi, Joanna; Milsom, Vanessa A.; Malcolm, Robert; O’Neil, Patrick M.

doi:10.1007/s13142-015-0353-9

Cited by 90 publications

(65 citation statements)

References 28 publications

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“…The goal of weight reduction to reduce the risk of cardiovascular disease needs to be understood by both, patients, and health care providers. A weight reduction of 5% is needed among obese or overweight adults for a signi cant reduction in all cardiovascular risks (29). These ndings may have practical implications for health care providers in addressing concerns and setting up appropriate weight loss goals in achieving the desired reduction in cardiovascular risks.…”

Section: Discussionmentioning

confidence: 99%

Towards Precision Health in Weight Reduction: Thematic Content Analysis of an Open-Ended Survey on Reasons Why Morbidly Obese Patients Want to Lose Weight.

Md-Yasin¹,

Ismail²,

Malek³

et al. 2020

Preprint

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Background: Addressing individuals’ motivation to lose weight among patients with morbid obesity is an essential entity in weight reduction. Failures to shift motivation into weight loss actions are common. These could be contributed by the inadequacy to identify and subsequently address the key reasons, that are of particular concern to the patient' individual needs. We aimed to understand the motivations better and identify the reasons why morbidly obese patients attending hospital-based weight management programmes (WMP) wanted to lose weight. Methods: The study used a qualitative approach to analyze part of a quantitative questionnaire of a more extensive study to understand factors influencing weight loss among morbidly obese patients. We used thematic content analysis to analyze responses from a self-administered open-ended question "What is the main factor why you want to lose your weight?”. A total of 225 new patients attending obesity clinics in two tertiary hospitals responded to the questionnaire. Results: Patients’ mean BMI was 45.6±8.05 kg/m2. Four themes emerged for the reasons why morbidly obese patients wanted to lose weight. Health was the most commonly inferred theme (84%). Patients were concerned about the impact obesity had on their health. Overcoming obesity was seen as a reward not just for physical health, but also for their psychological wellbeing. Patients regard being functional to care for themselves, their family members, as well as their religious and career needs as the next most crucial theme (25.8%). Patients raised the theme appearance (12.9%), especially with regards to wanting to look and feel beautiful. The last theme was perceived stigmatization for being morbidly obese as they were mocked and laughed at for their appearance (3.1%).Conclusion: Patients with morbid obesity in this study had expressed their main personal motivational reasons to lose weight. Concerns about the impact of morbid obesity on health, physical, social and obligatory function, appearance and perceived stigma warrant detailed exploration by the managing health professionals. Identifying and addressing these unique personal motivations in a focused approach is vital at the beginning and throughout a weight reduction program in this unique group.

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Section: Discussionmentioning

confidence: 99%

Towards Precision Health in Weight Reduction: Thematic Content Analysis of an Open-Ended Survey on Reasons Why Morbidly Obese Patients Want to Lose Weight.

Md-Yasin¹,

Ismail²,

Malek³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…We also included studies that reported the proportion of participants who achieved ≥ 5% weight loss at follow-up. This outcome was also collected because modest ≥ 5% weight loss is associated with reduction in cardiovascular risk among overweight and obese individuals [10,15,23]. …”

Section: Methodsmentioning

confidence: 99%

“…Research shows that even modest weight loss of 5–10% can reduce cholesterol levels, improve glycemic control, and lower blood pressure [10–12]. Extensive research supports lifestyle interventions focused on nutrition education and increasing physical activity participation for achieving weight loss in general patient populations [13–15].…”

Section: Introductionmentioning

confidence: 99%

Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: A systematic review and meta-analysis

Naslund

Whiteman

McHugo

et al. 2017

General Hospital Psychiatry

122

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Objective To conduct a systematic review and meta-analysis to estimate effects of lifestyle intervention participation on weight reduction among overweight and obese adults with serious mental illness. Method We systematically searched electronic databases for randomized controlled trials comparing lifestyle interventions with other interventions or usual care controls in overweight and obese adults with serious mental illness, including schizophrenia spectrum or mood disorders. Included studies reported change in weight [kg] or body mass index (BMI) [kg/m2] from baseline to follow-up. Standardized mean differences (SMD) were calculated for change in weight from baseline between intervention and control groups. Results Seventeen studies met inclusion criteria (1968 participants; 50% male; 66% schizophrenia spectrum disorders). Studies were grouped by intervention duration (≤ 6-months or ≥ 12-months). Lifestyle interventions of ≤ 6-months duration showed greater weight reduction compared with controls as indicated by effect size for weight change from baseline (SMD = − 0.20; 95% CI = − 0.34, − 0.05; 10 studies), but high statistical heterogeneity (I2 = 90%). Lifestyle interventions of ≥ 12-months duration also showed greater weight reduction compared with controls (SMD = − 0.24; 95% CI = − 0.36, − 0.12; 6 studies) with low statistical heterogeneity (I2 = 0%). Conclusion Lifestyle interventions appear effective for treating overweight and obesity among people with serious mental illness. Interventions of ≥ 12-months duration compared to ≤ 6-months duration appear to achieve more consistent outcomes, though effect sizes are similar for both shorter and longer duration interventions.

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“…A reduction in weight can have clinically significant health improvements. Achieving 5% to 10% weight loss is associated with reductions in cardiovascular risk factors, morbidity, and mortality, with some guidelines suggesting that weight change of 3% to 5% may lead to clinically meaningful health benefits . Behavioural changes in diet and physical activity can lead to weight reductions in individuals with excess weight and reduce the risk of comorbidities and chronic conditions and can be effective for long‐term weight reduction …”

Section: Introductionmentioning

confidence: 99%

A systematic review with meta‐analyses of text message‐delivered behaviour change interventions for weight loss and weight loss maintenance

et al. 2020

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Short Message Service (SMS)-delivered behaviour change interventions are frequently used to support weight management. This systematic review examines the effectiveness of SMS-delivered behaviour change interventions for weight management. Electronic databases were searched for randomised controlled trials (RCTs) comparing SMS-delivered adult weight management interventions to control groups, published between 1990 and 2018. Weight change was examined using random effects meta-analyses at intervention cessation and postintervention follow-up. Subgroup analyses examined intervention duration, SMS frequency, theory use, SMS interactivity, and SMS tailoring. Fifteen studies met inclusion criteria (2705 participants). For weight loss interventions (n = 12, 1977 participants), the mean difference in weight change was −2.28 kg (95% confidence interval [CI] −3.17 to −1.36 kg). No studies reported postintervention follow-up. For weight loss maintenance interventions (n = 3, 728 participants), the mean difference in weight change was −0.68 kg (95% CI, −1.31 to −0.05 kg), and postintervention follow-up (n = 2, 498 participants) effects were −0.57 kg (95% CI, −1.67 to 0.53 kg). No subgroup differences were found. SMS-delivered behaviour change interventions for weight loss led to significant small to moderate weight loss and weight loss maintenance compared with control groups. Evidence on long-term effects is limited. SMS-delivered behaviour change interventions are a potentially effective and scalable intervention option for obesity treatment.

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Effects on cardiovascular risk factors of weight losses limited to 5–10 %

Cited by 90 publications

References 28 publications

Towards Precision Health in Weight Reduction: Thematic Content Analysis of an Open-Ended Survey on Reasons Why Morbidly Obese Patients Want to Lose Weight.

Towards Precision Health in Weight Reduction: Thematic Content Analysis of an Open-Ended Survey on Reasons Why Morbidly Obese Patients Want to Lose Weight.

Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: A systematic review and meta-analysis

A systematic review with meta‐analyses of text message‐delivered behaviour change interventions for weight loss and weight loss maintenance

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