Effects of α-ethinyl estradiol (EE2) and diethylhexyl phthalate (DEHP) on growth performance, antioxidant status and immune response of juvenile yellow catfish Pelteobagrus fulvidraco

Effects of Di-(2-Ethylhexyl) Phthalate At Environmentally Relevant Concentrations On Oxidative Stress and Lipid Metabolism in Livers of Male Xenopus Tropicalis

“…1b (P < 0.05). The increase in HSI of the liver may be due to disturbed lipid metabolism and lipid accumulation (Meng et al 2018;Mo et al 2019). Above results indicated that the liver is one of the target organs for DEHP toxicity to male X. tropicalis.…”

Xenosteroids in aquaculture with special consideration to Lake Manzala (Northern delta lake, Egypt): Types, sources and mechanism of action

“…for 56 days showed significantly decreased total anti-oxidation capacity (TAOC), superoxide dismutase (SOD) and CAT activities and significantly increased malondialdehyde (MDA) level in the liver (Mo et al, 2019). Lower EE2 concentration (1ng/L) exposure in the same fish species induced significantly higher liver total anti-oxidative capacity and malondialdehyde content but no significant change in CAT or SOD activities (Chen et al, 2017).…”

“…Again, Zebrafish (D. rerio) male embryos exposed to 100 µg/L of BPS for 75 days showed significantly decreased body length and weight (Naderi et al, 2014). However, exposure of yellow catfish (Pelteobagrus fulvidracoto) to 1.0 μg/L EE2 and 1.0 mg/L DEHP for 56 days induced increased body weight, weight gain and hepatosomatic index (HIS), which was attributed to liver damage and fat accumulation (Mo et al, 2019). Similarly, juvenile yellow catfish (P. fulvidraco) exposed to 0.5 mg/L DEHP for 56 days induced a significant increase in feed intake, body weight and specific growth rate (Yuan et al, 2017).…”

“…Early studies implied that injected E2 could suppress both plasma and mucosal immunoglobulin M (IgM) levels and macrophages function, changing the innate immunity aspects in common carp and gilthead seabream (Cuesta et al, 2007). A more recent study on yellow catfish (P. fulvidraco) juveniles reported a significant decrease in phagocytic activity and respiratory burst activity with no change in 50% haemolytic complement activity and total immunoglobulin content following exposure to 1.0 μg/L EE2 and 1.0 mg/L DEHP for 56 days (Mo et al, 2019). Same fish species juveniles exposed to 1ng/L EE2 for 56 days showed significantly increased lysozyme activity, significantly decreased phagocytic indices, and non-significantly altered respiratory burst activity, total immunoglobulin nor 50% haemolytic complement activity (Chen et al, 2017).…”

COVID-19 discarded disposable gloves as a source and a vector of pollutants in the environment

“… Compound Structure Negative effect Organism Ref. PLASTICIZERS dimethyl phthalate (DMP) oxidative damages, disturb of the gene expression levels Zebrafish (Danio rerio) ( Cong et al, 2020 ) inhibited growth, cell inactivation, cell membranes damage Escherichia coli K12 ( Wang et al, 2019b ) prenatal exposure affects reproductive development Human males ( Suzuki et al, 2012 ) diethyl phthalate (DEP) reduced the average lifespan, decreased reproduction Caenorhabditis elegans ( Pradhan et al, 2018 ) histological structures damages of liver and kidneys, inhibition of cell proliferation Flounder (Paralichthys olivaceus) ( Xiao et al, 2018 ) diethylhexyl phthalate (DEHP) liver damage, ROS generation, lipid peroxidation, immunosuppression Catfish (Pelteobagrus fulvidraco) ( Mo et al, 2019 ) reduced the average lifespan, decreased reproduction Caenorhabditis elegans ( Pradhan et al, 2018 ) disruption of female fertility, hormones and ovarian folliculogenesis Mice ( Chiang et al, 2020 , Chiang and Flaws, 2019 ) utero exposure decreases anogenital distance and reproductive, poses reproductive hazard Human males ( Dorman et al, 2019 ) diisodecyl phthalate (DIDP) behavioral, enzymological, and oxidative stress, disruption in circadian rhythm liver and kidney damage, increase in levels of ROS Zebrafish (Danio rerio) ( Poopal e...…”