Electroencephalography and Clinical Neurophysiology

1972

DOI: 10.1016/0013-4694(72)90159-9

|View full text |Cite

|

Sign up to set email alerts

|

Effects of α-adrenergic blockers on visual evoked responses in rabbits

¹

,

²

,

William J. Giardina

³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

0

Mentioning

0

Contrasting

0

Year Published

1972

1972

1983

1983

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 7 publications

References 5 publications

Supporting

0

Mentioning

0

Contrasting

0

Order By: Relevance

Functional and morhological abnormalities induced by ouabain intoxication of the rabbit retina

¹

,

²

,

³

1983

Acta Neuropathol

View full text Add to dashboard Cite

Several researchers have recently used an intravitreal ouabain injection to induce a suitable model of experimental retinopathy and optic neuropathy in various animals. Ouabain administration into the vitreous body of rabbit causes an irreversible degeneration of the retinal layers and consequently of the optic nerve. The degeneration is proportional to the amount of injected drug. Electroretinographic recordings (ERG) show that these structural abnormalities are related to an inhibition of the electric retinal activity as the dose-dependent reduction of ERG waves amplitude has shown. Moreover, ERG and visual evoked responses (VER) measured at the same time evidence that the intravitreal injection of 1.7 nmol ouabain may block the impulse conduction along the optic nerve. This can be proved by the fact that 90 min after an ouabain injection VER disappears, while ERG is only partially reduced. These results are correlated with both morphological observation and autoradiographic studies on 3H-ouabain distribution in different retinal layers.

Functional and morhological abnormalities induced by ouabain intoxication of the rabbit retina

¹

,

²

,

³

1983

Acta Neuropathol

View full text Add to dashboard Cite

Several researchers have recently used an intravitreal ouabain injection to induce a suitable model of experimental retinopathy and optic neuropathy in various animals. Ouabain administration into the vitreous body of rabbit causes an irreversible degeneration of the retinal layers and consequently of the optic nerve. The degeneration is proportional to the amount of injected drug. Electroretinographic recordings (ERG) show that these structural abnormalities are related to an inhibition of the electric retinal activity as the dose-dependent reduction of ERG waves amplitude has shown. Moreover, ERG and visual evoked responses (VER) measured at the same time evidence that the intravitreal injection of 1.7 nmol ouabain may block the impulse conduction along the optic nerve. This can be proved by the fact that 90 min after an ouabain injection VER disappears, while ERG is only partially reduced. These results are correlated with both morphological observation and autoradiographic studies on 3H-ouabain distribution in different retinal layers.

Evidence that monoamines influence human evoked potentials

¹

,

²

1975

Brain Research

View full text Add to dashboard Cite

Effects of α-adrenergic blockers on visual evoked responses in rabbits

¹

,

²

,

³

et al. 1972

Electroencephalography and Clinical Neurophysiology

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Copyright © 2024 scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.