Effects of water extract ofCajanus cajanleaves on differentiation and function of primary osteoblasts and osteoclastsin vitro

Cissus quadrangularis Linn exerts dose‐dependent biphasic effects: osteogenic and anti‐proliferative, through modulating ROS, cell cycle and Runx2 gene expression in primary rat osteoblasts

“…). A number of studies have reported concentration‐ and time‐dependent effects of Cajanus cajan and Tinospora cordifolia extract on proliferation, osteogenic differentiation and mineralization of osteoblast model systems in vitro . Interestingly, our study also showed that effects of CQ extract on proliferation and differentiation of osteoblasts are both concentration‐ and time‐dependent.…”