Effects of Vitamins E and C on Freezed-Thawed Immature Mice Testis

Kushki, Davoud; Azarnia, Mahnaz; Khanipour-Khayat, Zahra; Beigi-Boroujeni, Mandana; Moradian-Majd, Afsaneh; Gholami, Mohammadreza

doi:10.17795/zjrms-7558

Cited by 2 publications

(1 citation statement)

References 24 publications

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“…There are some ways introduced to maintain quality of the germ cells undergoing freezing-thawing process and also the quality of sperms and other germ cells; for instance, antioxidants such as Na 2 SeO 3 , quersetine or other flavonoid compounds, magnesium sulfate or antioxidants in medical plants like ginger and onion, carrot seed extract ( 56 ) or water melon seed, chemical drugs like tramadol and adding vitamins C and/or D in vitro ( 32 , 42 - 58 ). Using melatonin is one of these methods.The quality of germ cells and sperms could be assayed by proteomic technics ( 59 ).…”

Section: Discussionmentioning

confidence: 99%

Protective effects of melatonin and ghrelin on spermatogenesis: A narrative review of the literature

Gholami

Ahmadi

Abaszadeh

et al. 2017

IJRM

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Spermatocytogenesis starts from lumens of seminiferous cords and after migration to the basal membrane ends to the lumens again. We attempt to review the protective effects of melatonin and ghrelin on Spermatocytogenesis and in particular on spermatogonial stem cells, as two rather newly-discovered hormones. Testicular freezing prior to chemotherapy and radiotherapy is one of the ways of preserving fertility in children with cancer. The freezing has two methods of slow-freezing (cryopreservation) and rapid-freezing (vitrification). Administration of melatonin can maintain the quality of the germ cells underwent such processes, as well as ghrelin, can protect germ cells from the toxicities secondary to ischemic injuries, and pathologic apoptosis. This review indicates that in vitro or in vivo administration of melatonin or ghrelin, could be effective to preserve fertilization and also they can be used in assisted reproductive technologies to improve the quality of sperms. Future original studies should be propelled toward human studies, of course with observing the ethics.

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Section: Discussionmentioning

confidence: 99%

Protective effects of melatonin and ghrelin on spermatogenesis: A narrative review of the literature

Gholami

Ahmadi

Abaszadeh

et al. 2017

IJRM

Self Cite

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Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review

Faramarzi

Khalili

Micara

et al. 2017

IJRM

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High implantation success following in vitro fertilization cycles are achieved via the transfer of embryos with the highest developmental competence. Multiple pregnancies as a result of the transfer of several embryos per cycle accompany with various complication. Thus, single-embryo transfer (SET) is the preferred practice in assisted reproductive technique (ART) treatment. In order to improve the pregnancy rate for SET, embryologists need reliable biomarkers to aid their selection of embryos with the highest developmental potential. Time-lapse technology is a noninvasive alternative conventional microscopic assessment. It provides uninterrupted and continues the survey of embryo development to transfer day. Today, there are four time-lapse systems that are commercially available for ART centers. In world and Iran, the first time lapse babies were born in 2010 and 2015, respectively, conceived by SET. Here, we review the use of time-lapse monitoring in the observation of embryogenesis as well as its role in SET. Although, the findings from our review support common use of time-lapse monitoring in ART centers; but, future large studies assessing this system in well-designed trials are necessary.

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Effects of Vitamins E and C on Freezed-Thawed Immature Mice Testis

Abstract: Background: The freezing of immature testis tissue and then the transplant of it can be considered as a major step in fertility preservation for young boys with cancer.

Cited by 2 publications

References 24 publications

Protective effects of melatonin and ghrelin on spermatogenesis: A narrative review of the literature

Protective effects of melatonin and ghrelin on spermatogenesis: A narrative review of the literature

Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review

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